Blog

Find our latest news stories and developments, and see below for an archive of our previous stories.

Earlier blog posts

2023

Special Introductory and PPI session on Breast and Cervical Health Literacy Research at St George's, University of London

11 JULY 2023

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For more info: https://www.knowyourlemons.org

About our meeting: PPI - Know Your Lemons Meeting, SGUL

2022

2022 Summer School: Genetics and Genomics in Medicine

21-22 OCTOBER 2022

For more info: https://www.summerschool2022.org

Khazanah Megatrends Forum 2022, Kuala Lumpur, Malaysia

3 & 4 OCTOBER 2022

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INNOVATION WITHOUT BORDERS: Science, Technology and Innovation in Malaysia and Beyond.

"Technology has always played a crucial role in economic growth and development. And, as we steer our way through this Perfect Storm, it is unquestionable that we will continue to rely on technology to manage Development and its Complexities. Technology comes in many forms but a key lesson remains that science, technology and innovation will result in whatever we seek out of it. Thus, we must understand, firstly, what are those technological developments that we see out there, and then, secondly, to what ends do we apply those means? "

For more info: https://kmf.com.my/programme_event/kmf2022/

Science Museum Latest Event - Can Home Testing Tackle Cervical Cancer?

25 MAY 2022

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"99.8% of cervical cancer is caused by persistent infection with high-risk human papillomaviruses (HPV), a common virus transmitted through sexual contact. When diagnosed, cervical cancer is one of the most successfully treatable forms of cancer, as long as it is detected early and managed effectively. Cancers diagnosed in late stages can also be controlled with appropriate treatment and palliative care."

2021

Great British Breakfast | New Year’s Eve 31st December

30 DECEMBER 2021

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Watch here: Great British Breakfast (at 1.36.30 minutes)

Two Jabs NotEnough Against Omicron, Shows UK Study. Should India Look At Boosters? Experts Explain

20 DECEMBER 2021

Screenshot 2022-01-06 at 12.20.23

Here’s what experts have to say:

Talking about this new study that highlights that two doses of vaccines are not enough to protect people against Omicron and booster dosage, Professor Sanjeev Krishna, St George’s University, London said,

We are now more than 18 months in this infection and we are thinking differently and we have different tools available to fight COVID-19. The analysis is that the two doses of Astra Zeneca does protect you from developing a severe disease AND hospitalisation for COVID-19. But we have seen a serious drop in effectiveness with Omicron variant. However, this on the other hand, is encouraging us to go ahead and develop the third dosage for COVID-19 and we may in the near future move forward towards mixING and matching of vaccines to fight COVID-19. The key message is let’s vaccinate people as much as possible and keep vaccinating them, as well as use other tools of protection.

2020

Sanjeev Krishna Supporting our research into coronavirus through the Coronavirus Action Fund

17 SEPTEMBER 2021

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Watch here: YouTube

Weak evidence for accuracy of Covid-19 antibody tests: Study

2 JULY 2020

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"A review of studies has found major weaknesses in the evidence base for diagnostic accuracy of Covid-19 antibody tests, particularly for point-of-care tests performed directly with a patient, outside a laboratory, and does not support their continued use. Serological tests to detect antibodies against Covid-19 could improve diagnosis and may be useful tools for monitoring levels of infection in a population, but it is important to formally evaluate whether there is sufficient evidence that they are accurate.the researchers said.

The study, published ín The BMJ, set out to determine the diagnostic accuracy of antibody tests for Covid-19."

DC (read more)

Antibody tests too unreliable to be used to judge coronavirus immunity levels, review finds

1 JULY 2020

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"Researchers found that if 100 people in 1,000 had been infected, lateral flow immunoassay tests would miss 34 cases.

Antibody tests miss up to one third of positive coronavirus cases and should not be used to judge immunity levels or guide medical decisions because they are so inaccurate, a major review has concluded.."

TELEGRAPH (read more)

Coronavirus Immunity in COVID-19 Patients May Not Last More Than Two Months, Finds New Study

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23 JUNE 2020

"Initial results from an antibody testing study have revealed that COVID-19 antibodies remain stable in the blood of the majority of infected individuals almost two months after diagnosis and possibly longer.."

HOSPIMEDICA (read more)

Why having Covid-19 might not lead to immunity

18 JUNE 2020

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"Being able to test whether people have developed protective antibodies against Covid-19 could be vitally important in helping combat the disease. Scientists in the UK working in conjunction with colleagues in Senegal have found that some people develop antibodies that last for two months but the scientists also warn that antibodies are not detectable in everyone exposed to the virus. Professor Sanjeev Krishna, one of the author’s of the paper from St George’s, University of London, outlines why not everyone who has Covid-19 develops immunity."

BBC SOUNDS (read more)

COVID-19 antibodies appear to last for at least two months

17 JUNE 2020

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"COVID-19 patients have been found to carry antibodies to the coronavirus for almost two months after falling sick, in a preliminary study. However, it is unclear whether the antibodies could protect the patients from being re-infected.."

SCIENCE FOCUS (read more)

Studies on COVID-19 antibody response undermine US “herd immunity” policy

16 JUNE 2020

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"The unstated but nonetheless official US government policy toward coronavirus is “herd immunity”—letting the pandemic rip until so many people have survived the infection that their immunity will block further spread. This policy is homicidal, in the literal sense of the word. The federal and state governments are allowing tens of millions to be infected by a disease which will kill a large number of them, perhaps millions, rather than undertake the systematic campaign of testing, contact tracing and isolating those infected or exposed, which would halt the spread of the disease before it rages entirely out of control.."

WSWS (read more)

Coronavirus immune response ‘may remain stable for two months after diagnosis’

15 JUNE 2020

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"The immune response to coronavirus may last for two months after diagnosis, new research suggests.

Results from an antibody testing study have revealed that Covid-19 antibodies remain stable in the blood of the majority of infected people almost two months after diagnosis, and possibly longer.

Antibodies are produced by the immune system when it is being attacked in order to destroy substances which carry disease.

The study also found that antibodies were not detectable in everyone exposed to the virus, leading to questions about how best to interpret antibody viral tests.."

YAHOO!FINANCE (read more)

COVID-19 antibody test validated by LSTM researchers ready for manufacture and distribution

04 JUNE 2020

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"LSTM is delighted to announce that the professional-use rapid diagnostic test for COVID-19 developed by Mologic Ltd has been certified with a CE mark and is ready for manufacture and global distribution, following successful independent validation by researchers at LSTM and St George’s, University of London."

LSTMED (read more)

St George's Vaccine Trial Opens To Over 55s

27 MAY 2020

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"The next phase of the coronavirus vaccine trial began at St George’s Hospital last weekend, as recruitment opens up to participants from older age groups, including those aged 56-69 and 70 and over.

The team is very keen to recruit participants from the local area.

This part of the study will assess the immune response to the vaccine in people of different ages, to find out if there is variation in how well the immune system responds in older people."

WANDSWORTH SW18.COM (read more)

Professor of Molecular Parasitology and Medicine, Sanjeev Krishna. Experts are working as quickly as they can to safely find a vaccine

22 MAY 2020

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"London coronavirus: St George's Hospital experts still 'several months' away from knowing if coronavirus vaccine works

The team at St George's Hospital is now recruiting volunteers over the age of 55 to test it

The next phase of the coronavirus vaccine trial begins at St George's Hospital this weekend, as recruitment opens up to participants from older age groups, including those aged 56-69 and 70 and over.

The team is very keen to recruit participants from the local area.

This part of the study will assess the immune response to the vaccine in people of different ages, to find out if there is variation in how well the immune system responds in older people."

MY LONDON NEWS (read more)

Expert advice on when lockdown might end

18 MAY 2020

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"How do we avoid a second peak of Covid-19 cases?

We need efficient application of tried-and-tested measures to break the chains of transmission, using the best technologies available where they are most needed. Other ways to reduce risks include maintaining social distancing and limiting the size of gatherings. Although there have been questions about wearing masks, it is a simple and cost-effective intervention that is becoming more socially acceptable in this country.”

Professor Sanjeev Krishna from St George’s, University of London, as told to Katie Strick."

EVENING STANDARD (read more)

Prof Sanjeev Krishna: Challenge Is To Reduce Risks Of Bad Outcome In Populations That Are Vulnerable

7 MAY 2020

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"Speaking to Zakka Jaocb on India's COVID-19 challenge, Prof Sanjeev Krishna said, "The second challenge is, how to you reduce the risks of bad outcome in populations that are vulnerable."

Watch here: CNN NEWS 18

SARS-CoV-2 Test Kit from QuantuMDx offers High Accuracy Test Results in 70 Minutes

2 MAY 2020

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"Sanjeev Krishna, Professor of Molecular Parasitology and Medicine at St George’s, University of London, said: “It’s universally acknowledged that one of the most urgent needs to help us control and hopefully eliminate the COVID-19 pandemic are good diagnostic tests. We need a test that can diagnose the disease quickly and accurately, while being available and affordable for all healthcare systems. This test is very much aiming to address those needs so we can control the infection with greater precision.” An application has been made to the U.S FDA for use under Emergency Use Authorisation and QuantuMDx expects to attain CE-IVD mark by mid-May. In addition, QuantuMDx will apply for World Health Organization ‘Emergency Use Listing’ listing."

ONE NEWS PAGE: (read more)

Breaking News: Newcastle business has today launched its sensitive SARS-CoV-2 test, which delivers a result in approx 70 minutes

1 MAY 2020

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"QuantuMDx Group Limited is an ambitious North East business, dedicated to making diagnostic technologies so that diseases can be detected and treated earlier, and transmission eradicated.

Today it has announced the launch of a sensitive test for laboratory use, which can detect the virus which causes COVID-19 within approximately 70 minutes.

Teaming up with British manufacturing partner Biofortuna Limited, QuantuMDx has been able to scale-up production capability to initially 2 million tests per week and with the potential to scale up to 3 million tests per week by introducing further automation within the manufacturing process..”

HIGH LIFE NORTH: (read more)

NEWCASTLE FIRM LAUNCHES COVID-19 TEST WITH CAPACITY FOR 2 MILLION TESTS PER WEEK

1 MAY 2020

Screenshot 2021-05-25 at 10.35.35 "Global life sciences and diagnostics developer, QuantuMDx has today (May 1) launched a COVID-19 test for laboratory use, which delivers results in approximately 70 minutes.

Sanjeev Krishna, professor of molecular parasitology and medicine at St George’s, University of London, is working closely with QuantuMDx on its diagnostic test.

He said: “It’s universally acknowledged that one of the most urgent needs to help us control and hopefully eliminate the COVID-19 pandemic are good diagnostic tests.

“We need a test that can diagnose the disease quickly and accurately, while being available and affordable for all healthcare systems. This test is very much aiming to address those needs so we can control the infection with greater precision.”

NORTH EAST TIMES MAGAZINE: (read more)

QuantuMDx Launches Rapid, Sensitive SARS-CoV-2 Test

1 MAY 2020

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"NEWCASTLE UPON TYNE, UK, 1 May 2020. QuantuMDx Group Limited, a UK-based life sciences company developing transformational point-of-care molecular diagnostics, today announces the launch of its sensitive SARS-CoV-2 assay for laboratory use, which delivers a result in approximately 70 minutes."

“It’s universally acknowledged that one of the most urgent needs to help us control and hopefully eliminate the COVID-19 pandemic are good diagnostic tests. We need a test that can diagnose the disease quickly and accurately, while being available and affordable for all healthcare systems. This test is very much aiming to address those needs so we can control the infection with greater precision.”

Sanjeev Krishna, Professor of Molecular Parasitology and Medicine at St George’s, University of London

INTRADO: (read more)

UK company hopes to mass produce home antibody testing kits

17 APRIL 2020

Screenshot 2021-05-25 at 10.43.12 "Scientists are racing to develop antibody tests that can tell people if they have had Covid-19 and may be safe to go back to work. One UK company may be close to an answer. CNN's Nick Paton Walsh reports."

CNN BUSINESS: (watch here)

A genetic predisposition for Cytokine Storm in life-threatening COVID-19 infection

12 APRIL 2020

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"Abstract The COVID-19 pandemic is a cause of serious morbidity and mortality and is placing a significant burden on healthcare systems globally. The clinical manifestations of COVID-19 disease form a wide spectrum, from mild symptoms to life threatening disease. A small subset of patients develop Cytokine Release Syndrome (CRS)/Cytokine Storm (CS) that results in hyper inflammation, clinical deterioration and multi-organ failure. There is growing evidence that Interleukin-6 (IL-6) is a central mediator of CS. Evidence of an inflammatory Kawasaki-like syndrome in children with severe COVID-19 is also emerging. Familial Mediterranean Fever (FMF) and Glucose-6-phosphate Dehydrogenase (G6PD) deficiency are 2 common gene polymorphisms that predispose to hyper inflammatory states. Countries with high mortality rates for COVID-19 deaths (such as Spain, Italy and France) or the Middle East (Iran) also have a high number of carriers of mutations in the Mediterranean Fever gene (MEFV), which causes Familial Mediterranean Fever (FMF).."

OSFPREPRINTS: (read more)

Here’s How The UK Plans To Go From 16,000 Tests A Day To 100,000 By The End Of The Month

10 APRIL 2020

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"Professor Sanjeev Krishna, who is also working on an antibody test with the company Mologic, said: “You can only really make decisions on how to manage this pandemic once you’ve got some figures in place on who’s had it, who’s in the process of having it and who is at risk of getting it. And if you need to make very targeted interventions to reduce upsurge in the NHS, to let society get back into some sort of regular routine, you’re going to have to rely on good testing.”

Antibody tests are already being used as part of a research programme operated by Public Health England at Porton Down, the government’s high-security lab campus in Wiltshire. They are testing blood samples of the population — 800 so far — to better understand the rate of infection and how the virus is spreading across the country. But the goal is to be able to do this on a mass scale."

BUZZFEED NEWS: (read more)

Med Sci Life

9 APRIL 2020

Screenshot 2021-05-25 at 10.55.38 "Professor Sanjeev Krishna works on infectious diseases at @StGeorgesUni & is co-leading the university's switch to focus entirely on #coronavirus. But back in January, we visited him at home to find out about the man behind the work... #medscilifehttps://medscilife.org/stories/sanjeev-krishna/"

THE ACADEMY OF MEDICAL SCIENCES: (read more)

St George’s Hospital pauses research to focus on coronavirus cure and testing

6 APRIL 2020

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"A university hospital has paused all its research to focus full-time on finding a coronavirus cure and testing patients.

St George’s, University of London, partnered with St George’s Hospital in Tooting, is working to understand the biology of the virus and the human body’s response to it.

Dr Tim Planche, who is leading the project alongside Professor Sanjeev Krishna, said: “Without testing and samples, you’re fighting coronavirus blind.”

LONDON NEWS ONLINE: (read more)

St George's, University of London focuses entire research on tackling coronavirus

3 APRIL 2020

"St George's, University of London, the UK's specialist health university, is focusing all its ongoing research on tackling coronavirus (COVID-19).

While other research on site has been paused, the University will remain open for researchers working on clinical trials and diagnostic tests for the disease, as well as those looking to understand the underlying biology of the virus and the body's immune response. The first trial led by the University to receive ethical approval is the collection of clinical samples from COVID-19-infected patients. These samples will initially be used to evaluate a rapid antibody test designed to tell people if they have coronavirus or not.

This project will be led by Professor Sanjeev Krishna and Dr. Tim Planche from the Institute of Infection & Immunity at St George's, University of London. The test, being developed by the company Mologic, has received funding from The UK Department for International Development (DFID) and The Wellcome Trust. Achieving ethical approval for this trial brings the test even closer to being used across healthcare systems.”

London coronavirus: The South London university that's now doing nothing else but searching for a cure to coronavirus

3 APRIL 2020

"St George's, University of London is working with St George's Hospital in Tooting on clinical trials and tests.

A London university is to move all of its research to tackling coronavirus.

St George's, University of London, which is partnered with St George's Hospital in Tooting, will now focus on working on clinical trials and tests for the disease.

Other research on the site has been paused so researchers can work to understand the biology of the virus and the human body's response to it.

Dr Tim Planche, who is leading the project alongside Professor Sanjeev Krishna, said: "Without testing and samples, you’re fighting coronavirus blind."

St George’s, University of London, which is partnered with St George’s Hospital in Tooting, will now focus on working on clinical trials and tests for the coronavirus.

3 APRIL 2020

"Other research on the site has been paused so researchers can work to understand the biology of the virus and the human body’s response to it.

Dr Tim Planche, who is leading the project alongside Professor Sanjeev Krishna, said: “Without testing and samples, you’re fighting coronavirus blind.” The first trial will involve collecting clinical samples from Covid-19-infected patients. These samples will first be used to evaluate a quick antibody test to tell people if they have coronavirus or not. The clinical samples collected from patients at St George’s Hospital as part of the trial will also be used to carry out further investigations into the biology of coronavirus and how it can be treated."

Conversation about Resistance - Novartis, Basel, Switzerland

5 FEBRUARY 2020

WEBSITE (read more)

Geneva Blockchain Congress

20 JANUARY 2020

"From Lab to Market through Ethics, Regulation and Governance"

WEBSITE (read more)

2019

TT4CL 2nd Partners Meeting, Nijmegen, The Netherlands

27 - 28 NOVEMBER 2019

"A simple oral treatment for the neglected disease cutaneous leishmaniasis Many diseases that are not life-threatening in developed countries, do not receive the resources and attention required to investigate prevention, treatment or cure. Cutaneous leishmaniasis (CL), caused by a parasite transmitted via infected sand flies, is one among them. Infections are common in low-income populations of developing regions. Producing ulcers, sometimes up to 200, on exposed parts of the body, CL can leave permanent scars that are often the source of extreme social prejudice. TT4CL is working hard to bring a promising oral treatment for CL into clinical trials. Registration with regulatory agencies requiring proof of conformance to stringent safety, efficacy and tolerability requirements could change the lives of millions of people globally."

AFRICAN CONGRESS FOR CLINICAL TRIALS

10 - 14 NOVEMBER 2019

"ACCT is an annual meeting involving researchers and clinical trial experts, health policy-makers, health professionals, as well as investors, entrepreneurs and civil society.

The aim is to bring together this research community and all its partners, but especially to create a meeting place for African society as a whole, including ethicists, regulatory bodies, health policy-makers, entrepreneurs and social organizations working on public health issues.

In addition, ACCT aims to help develop a learned society for clinical trials in Africa, and to reinforce a framework for collaboration with international partners."

FIND SAC MEETING - Geneva

7 - 9 OCTOBER 2019

"FIND is the Foundation for Innovative New Diagnostics. We are a global non-profit organization driving innovation in the development and delivery of diagnostics to combat major diseases affecting the world’s poorest populations..

FIND is a WHO Collaborating Centre for Laboratory Strengthening and Diagnostic Technology Evaluation. "

11th European Congress on Tropical Medicine and International Health 2019 (ECTMIH), Liverpool, UK

16 - 20 SEPTEMBER 2019

"The first ECTMIH took place in 1995 in Hamburg and was organised by a small community of experts in tropical medicine and international health.

Since then, the main objective of the Congress has remained the same: providing a platform for state-of-the-art updates, developments and breakthroughs in the field of tropical medicine and global health...."

TT4CL Partners Kick - off Meeting, London, St. George's University

4 JULY 2019

"Professor Sanjeev Krishna and colleagues are heading a consortium that has been awarded EUR3.75 million to develop a treatment for one of the world’s most neglected tropical diseases, leishmaniasis..."

Artemisinin for Malaria Control and Elimination: History and Future, Beijing, China

14 JUNE 2019

"Artemisinin's growing importance in medicine: Repurposing for Cancer"

Sanjeev Krishna visited Beijing University at the invitation of WHO between the 12th– 14thJune 2019. He was invited to speak on “Artemisinin’s growing importance in medicine: repurposing for cancer”, a subject that has become of great interest to Chinese investigators as well as the Government. The visit was very well received, and included an interview with Xinhua (http://www.techweb.com.cn/news/2019-06-17/2740267.shtml) as well as a personal meeting with the Nobel Laureate Tu Youyou in her flat.

World Malaria Day

25 APRIL 2019

"Professor Sanjeev Krishna discusses his paper that will be featured in the New England Journal of Medicine discussing the effectiveness of the anti-malarial drugs artemisinins. "

Watch on YouTube

Read the paper

Watch on CGTN NEWS

Charity Fundraising Event at The Mango Tree

12 MARCH 2019

"Charity Fundraiser in support of St George's Hospital Charity and the NeoART Trial researching innovative cures for bowel cancer.

PRECISE Annual Meeting 2019 - Johannesburg, South Africa

5 FEBRUARY 2019

TT4CL, HORIZON 2020 THE EU'S RESERCH AND INNOVATION PROGRAMME..

Innovative diagnostic test could revolutionise cervical cancer screening

23 JANUARY 2019

Coinciding with Cervical Care Prevention Week, Professor Sanjeev Krishna and Dr Henry Staines at St George’s University of London are working on a field study to fine-tune an exciting new method of human papilloma virus testing that could revolutionise care for women in low and middle income countries.

2018

Meet the Experts Transporter Conference, Budapest

25 and 26 - 27 APRIL 2018 FEBRUARY

"This April we invite you to the 8th Meet the Experts Transporter Conference in Budapest. Since 2014 the Meet the Expert Transporter conferences have been a continuing success. Hundreds of attendees have enjoyed talks from the best Transporter Scientists in the world. The conferences cover a wide range of topics, far beyond the role of transporters in Drug-Drug Interactions, which other transporter meetings mostly focus on. Previous meetings included symposia such as Methods and Models, The Physiological Function of Transporters, The Role of Transporters in Disease, Transporter-Enzyme Interplays, Transporter interactions of natural and synthetic compounds, Transporters and biomarkers and Transporters and regulation."

Roundtable: Can the UK save it's National Health Service?

21 FEBRUARY 2018

"Sick and incurable or a model of perfect health? Britain's NHS - the National Health Service - costs almost $150 billion dollars a year. Who's going to tell this patient it's run out of time? There are many who argue that as the NHS is still sometimes called the best in the world - it's time to re-assess what Britain offers those who need treatment - either occasionally or much of the time. What was once innovative, is now creaking with age. There are fitter, leaner and cheaper models out there. In the UK, is it time to think again?"

Nairobi - PRECISE Network kick off meeting

29 - 30 JANUARY 2018

"PRECISE Network kick off meeting"

Roundtable: What medical breakthroughs are imminent?

18 JANUARY 2018

"Medical breakthroughs that improve lives and save them - what progress is being made towards solving the world's biggest health problems? For decades scientists have been working on cures for common deadly diseases like cancer and Alzheimer’s. Is modern technology helping to speed things up? What medical breakthroughs will this year bring? At the Roundtable was Zahid Latif, from the Life Sciences Organisation; Ivan Wall, Professor of Regenerative Medicine at Aston University; and Sanjeev Krishna, Professor of Molecular Parasitology and Medicine at St George’s, University of London. Roundtable is a discussion programme with an edge. Broadcast out of London and presented by David Foster, it's about bringing people to the table, listening to every opinion, and analysing every point of view. From fierce debate to reflective thinking, Roundtable discussions offer a different perspective on the issues that matter to you. Watch it every weekday at 15:30 GMT on TRT World."

ROUNDTABLE

2017

WHO - Prevention Diagnosis and Treatment Global Malaria Programme - TEG Meeting

11 - 12 DECEMBER 2017

"The Malaria Chemotherapy TEG Meeting"

Wellcome DBT India Alliance

6 - 9 NOVEMBER 2017

"The Wellcome Trust/DBT India Alliance is an £160 million initiative funded equally by the Wellcome Trust, UK and Department of Biotechnology, India. The broad aim of the India Alliance is to build excellence in the Indian biomedical scientific community by supporting future leaders in the field."

Charity fundraiser event in support of Research for Bowel cancer at the Barracuda Club

4 NOVEMBER 2017

"We cordinally invite you to join us at the Barracuda Club on Saturday 4th November 2017 to help us fundraise for a charity that supports clinical research for bowel cancer. "

ECTMIH 2017: New Clinical Developments of Antimalarials

16 - 20 OCTOBER 2017

"The main objective of ECTMIH2017 is to provide a platform for state-of-the-art updates and recent breakthroughs in the field of tropical medicine and global health. Plenaries, scientific sessions and symposia will deal with a broad range of biomedical, clinical and epidemiological updates. Global infectious diseases (malaria, tuberculosis, HIV/AIDS) as well as tropical and poverty-related health problems will be put in the spotlight..."

FIND Scientific Advisory Committee - Geneva

21 - 22 SEPTEMBER 2017

The Academy of Medical Sciences -

'Strengthening clinical research capacity in LMICs'

3 - 4 JULY 2017

"1. Improve clinical research mentoring opportunities, both institutionally and individually

2. Academy networks that can offer learning and support opportunities

3. Support for LMICs to define their own clinical research agendas

4. Strengthened national and regional networks

5. Increased health research funding from national governments

6. Advocacy and research diplomacy to demonstrate the impact of clinical research

7. Improved career pathways for clinical research in LMICs

For more information about work in these areas, please visit:

www.acmedsci.ac.uk/grants-and-schemes

CLINICAL RESEARCH CAPACITY WORKSHOP REGIONAL PRESENTATION pdf.

Wellcome DBT India Alliance

16 - 20 MAY 2017

APAM UCL 2017 - THE 111TH ANNUAL MEETING OF THE ASSOCIATION OF PHYSICIANS OF GREAT BRITAIN & IRELAND

6 - 7 APRIL 2017

" Making the U.K. a great place to do research - opportunities and challenges. .."

KEYSTONE SYMPOSA - MALARIA: FROM INNOVATION TO ERADICATION

19 - 23 FEBRUARY 2017

" The evidence base and research agenda for malaria elimination and eradication are fast-evolving. Of foremost concern is the threat of resistance of the mosquito to pyrethroid insecticides and emerging data showing multi-drug resistance in Southeast Asia. .."

3rd Diagnostics in the Developing World Conference: 23rd - 25th Jan 2017

23 JANUARY 2017

" A conference series that brings together clinicians, academics, epidemiologists, engineers and key stakeholders who have a keen interest in the area of diagnostics for the developing world. This conference will form collaborations between a unique group of stakeholders from across the globe to tackle the key issues and challenges being faced, such as the slow pace of diagnostic development, regulatory approval and technology adoption bottlenecks..."

2016

ICVS International Seminars, Braga

18 NOVEMBER 2016

"The ICVS International Seminar Series” are opened to the entire academic and scientific communities from within and outside the ICVS, giving participants a unique opportunity to gain better understanding and discuss the more recent scientific breakthroughs.."

Wellcome DBT India Alliance

7 - 12 NOVEMBER 2016

"The Wellcome Trust/DBT India Alliance (India Alliance) is an £80 million partnership, co-funded by the Wellcome Trust, UK and the Department of Biotechnology, Government of India. Operated as an independent charity in India, the India Alliance provides a unique programme of research fellowship schemes, to build research capacity by supporting biomedical scientists at key stages of their careers in India.."

2016 BioInfect Conference

3 NOVEMBER 2016

"A major 1-day conference looking at the critical issues relating to the development of new anti-infectives and the endemic problem of resistance.

Antimicrobial resistance occurs when microorganisms such as bacteria, viruses, fungi and parasites change in ways that render the medications used to cure the infections they cause ineffective. When the microorganisms become resistant to most antimicrobials they are often referred to as “superbugs”. This is a major concern because a resistant infection may kill, can spread to others, and imposes huge costs to individuals and society.."

Charity Sunday High tea fundraiser event in support of Research for

Bowel cancer

16 OCTOBER 2016

"We cordinally invite you to join us at the Barracuda Club on Sunday 16th October 2016 t help us fundraise for a charity that supports clinical research for bowel cancer. "

Brexit debate - What would leaving the EU mean for science and medicine?

19 MAY 2016

"The EU referendum on UK membership on Thursday, 23 June 2016 will decide whether to leave or remain in the European Union. What could staying or leaving mean for science and medicine?"

Chinese lunch fundraiser event

17 JANUARY 2016

"Lunch at Feng Shang floating chinese restaurant in Regent's Park to raise funds for a new trial into whether an anti-malaria drug could be used to treat bowel cancer. "

2015

Campaign aims to fund new bowel cancer drug trial

6 NOVEMBER 2015

"A campaign has been launched to raise funds for a new trial into whether an anti-malaria drug could be used to treat bowel cancer.

Doctors at St George's Hospital, in Tooting, south London, want to investigate whether the drug Artesunate could be used in cancer treatment. The drug is commonly used to treat malaria, however lab tests have suggested it can kill cancer cells.

Doctors have already undertaken a small scale study with promising results.

BBC London's Emma North spoke to cancer patient Dorothy Bradshaw, Prof Devinder Kumar

and Prof Sanjeev Krishna. "

Antimalarial Artemisinins Against Cancer

SEPTEMBER 2015

"When Dorothy Bradshaw agreed to take part in a clinical trial for a potential bowel cancer drug five years ago she had very low expectations..."

CISA- Angola

28 - 30 SEPTEMBER 2015

Prof. Sanjeev Krishna participated as an invited talker in a seminary organized in partnership with CISM (Manhiça –Moçambique) and CISA, in Angola from 28 to 30 September

Seminary - Health Investigation Center of Angola and Health Investigation Center of Mazambique

Crowdfunding Campaign Begins!

22 SEPTEMBER 2015

Launch of crowdfunding campaign for Artesunate in the treatment of bowel cancer (22nd September 2015 New Malden).

From left to right: Hajnalka Kovacsevics, Dr. Yolanda Augustin, Dr. PanPantziarka , Prof. Sanjeev Krishna, Gary Douch, Dr. Gayathri Perera, Prof. Devinder Kumar, Dr. Deepika Kassen

THE TELEGRAPH

Interview with Dorothy Bradshaw, whose tumour stopped growing after two weeks of taking the antimalarial drug Artesunate

ECANCER NEWS

Crowdsourcing a cancer drug: how the public can bring a new (old) drug to trial

Can Artesunate, an antimalarial drug, provide an effective and affordable treatment for Bowel Cancer

DTRA 2015 rVSV Filovirus Vaccine Sceince Review Meeting

16 - 17 JULY 2015 WASHINGTON (attended by Prof. Sanjeev Krishna)

This meeting provided a forum for those developing rVSV vaccines for filoviruses to have an open exchange of information about their recent, ongoing, or planned work. Clinical and non-clinical studies will be discussed.

This meeting will bring together government, academic, and industry researchers who involved in both basic and applied research on this vaccine. Through a mix of invited talks and discussion:

Examine clinical studies
Examine non-clinical studies including safety and efficacy efforts
Elucidate potential pathways to licensure including immune correlates and animal rule
Discuss essential data needs including safety studies and GMO issues
Confer approaches and challenges to development to multivalent vaccine including, virus interactions, antivector immunity, and multigenic vector construction
Highlight S&T areas for potential cost effective future investments

NIBSC INTERNATIONAL WORKSHOP: Development of serological and PCR assays for the detection of viruses in the Ebola virus family

5 - 6 MARCH 2015

In March, two of our researchers involved in the clinical trials of VSV-ZEBOV-GP anti-Ebola virus vaccine, Rebekah Burrow and David Clark, attended an international workshop at the National Institute of Biological Standards and Control; the meeting focused on the development of serological and PCR assays for the detection of viruses in the Ebola virus family. Assays for determining the human immune response to Ebola virus disease and novel anti-Ebolavirus vaccinations were also topics of discussion. The meeting was also attended by representatives from institutions around the world including: WHO, NIH, CDC, HPA, MSF and MHRA. The meeting established a timeline for the preparation, distribution and evaluation of reagents and protocols to support the standardisation of immunological and diagnostic assays for Ebola virus.

NIH (USA National Institutes of Health), CDC (USA Centers for Disease control and Prevention), HPA (UK Health protection Agency), MSF (Médecins Sans Frontières), MHRA, Medicines and Healthcare products Regulatory Agency, WHO (World Health Organisation)

Handheld DNA analyser to tackle 125,000 African infant deaths a year

27 APRIL 2015

To mark World Malaria Day, it has been announced that a three-year project developing a handheld DNA analyser to tackle drug resistant malaria is nearing completion.

Medical technology developer QuantuMDx and St George’s, University of London are developing Q-POC™ as part of a three-year €5.2m (£4m) development project..

25th ECCMID, Copenhagen, Denmark, 25 - 28 April 2015

27 APRIL 2015

Sanjeev Krishna - Rapid diagnostics for malaria and other parasitic diseases | Oral Presentation #S090. State-of-the-art in rapid diagnostics.

Published by ESCMID 27 April, 2015

This must be the year we beat Ebola in West Africa

2 JANUARY 2015

Sanjeev Krishna receives funding from the World Health Organisation and the Wellcome Trust as part of a consortium to develop a vaccine against Ebola.

Carwyn Hooper does not work for, consult to, own shares in or receive funding from any company or organisation that would benefit from this article, and has no relevant affiliations.

Published by The Converstation 2 January, 2015

2014

Could leading anti-malarial be used as an experimental treatment for bowel cancer?

2 DECEMBER 2014

While the medical world is transfixed by the urgency of finding and testing new potential treatments for Ebola, the House of Lords is wrestling with how to employ treatments that have not been tested for a particular use, but which could bring some benefit to dying patients.

Ebola pioneering mission among media highlights

1 DECEMBER 2014

BBC World

27 OCTOBER 2014

Prof Sanjeev Krishna gives his views on the latest Ebola news and includes information about a new trial he is working on in Africa.

Experts join crucial Ebola vaccine test on humans

17 OCTOBER 2014

Professor Sanjeev Krishna, of St George’s University of London’s Institute for Infection and Immunity, said: “We know how urgent it is for an effective vaccine for humans to be tested, so we can help to stop the horrifying impact of this deadly disease.

“It is a measure of the global need, as well as the responsiveness of our collaborative group, that this clinical trial is forging ahead so speedily with the first volunteers recruited in Gabon in November."

Challenges in Malaria Research: Core science and innovation - Program

23 SEPTEMBER 2014

BioMed Central, in conjunction with its journals Malaria Journal and Parasites & Vectors, is hosting the third malaria conference “Challenges in Malaria Research: Core science and innovation” in Oxford, UK from 22-24 September 2014.

New issues in clinical malaria and pathology, 23 September

14:30 Science and innovation in malaria diagnostics

Sanjeev Krishna, St George’s, University of London, UK

Published by The BioMedCentral September, 2014

The NANOMAL PROJECT UPDATED WEBSITE IS ON LIVE NOW

19 SEPTEMBER 2014

The Future of malaria diagnosis

Our FP7 European Union funded NanoMal Consortium is developing a handheld laboratory that will deliver complex malaria diagnostics in minutes for a few dollars in any setting across the globe.

Making malaria elimination possible

Our handheld laboratory will provide frontline healthworkers with the definitive tool to diagnose, manage and monitor malaria and drug resistance.

Results in 10-15 minutes

Malaria diagnosis & drug resistance testing

Directs right first time prescribing

Handheld, user friendly, low cost

Mobile data connection

CHECK OUT NANOMAL.ORG WEBSITE

Published September 19, 2014

Professor joins World Health Organisation's ebola crisis summit..

4 - 5 SEPTEMBER 2014

Consultation on potential Ebola therapies and vaccines

Professor Sanjeev Krishna joined more than 100 scientists at an emergency meeting of the World Health Organisation (WHO) to discuss new measures to tackle the Ebola virus.

Professor Krishna said: "“Up till now, there hasn’t been much clinical experience of Ebola because it has mercifully presented in limited outbreaks. However, we are in an unforeseen epidemic now, which has gone well beyond an outbreak.

"It is difficult to say how many will die in appalling conditions before this comes under control, but WHO is coordinating several initiatives to speed up ways to control Ebola

MEETING OUTCOMES

Published by WHO, SEPTEMBER 5, 2014

'Milestone' for child malaria vaccine

By Smitha MundasadHealth reporter, BBC News

29 JULY 2014

Prof Sanjeev Krishna of St George's University of London who was not involved in the research but reviewed the paper for the journal said: "This is a milestone. The landscape of malaria vaccine development is littered with carcasses, with vaccines dying left, right and centre.

"To get to this stage is very encouraging indeed. We eagerly await the next results to see how long-lasting protection is and whether a booster adds further potential...

Published by The BBC, JULY 29, 2014

To fight malaria, we now have genetic weapons that can track and kill

16 JUNE 2014

Every year malaria kills more than 600,000, which is a little less than the population of Bhutan. There are some simple solutions to control the disease, but keeping the numbers of mosquitoes with malarial parasites down remains a challenge.

Published by The Conversation, June 16, 2014

Interview with Sanjeev Krishna, Ph.D.

5 MAY 2014

Published by Emory MaHPIC, Youtube, on May 5, 2014

Malaria diagnosis: past, present and future

25 APRIL 2014

To mark World Malaria Day, we interviewed Professor Sanjeev Krishna, whose wide-ranging research has spanned clinical trials of antimalarial treatments, mechanisms of drug resistance, and identification of the likely target of artemisinin, among much else.

Here's what he had to say...

Published by BioMed Central, Youtube, on Apr 25, 2014

Welcome to our new website!

01 MARCH 2014

We’ve redesigned our website and produced a new group brochure.

We hope the new site provides some insight into our achievements over the past two decades and the exciting directions of our current work. A PDF of our group brochure can be downloaded here.

Congratulations to Elaine Warburton OBE

03 JANUARY 2014

The CEO of our Nanomal partner company has been awarded an OBE in the New Year Honours list.

We were delighted to hear that Elaine Warburton, Group CEO of QuantuMDx, technology partners in our Nanomal malaria diagnostic project, has been awarded an OBE for services to health innovation. We are making excellent progress with our malaria diagnostic, and hope to begin field trials later this year.

Reflections on PfATP6 as the target for artemisinins

01 JANUARY 2014

Our review of PfATP6 and the mode of action of artemisinins has been published in the January 2014 issue of Trends in Pharmacological Sciences.

As well as reviewing the evidence that PfATP6 is a key target for artemisinins, we discuss the wider context of calcium regulation during parasite development and implications for artemisinin resistance. The abstract of the article can be accessed here.

2013

BIOME

19 NOVEMBER 2013

Sanjeev Krishna is a Section Editor for BMC Infectious Diseases, a journal dedicated to research on all aspects of the prevention, diagnosis and management of infectious and sexually transmitted diseases in humans.

Published by BioMed Central, Youtube, on Nov 13, 2013

Controlling mosquito sex lives is one way to fight malaria

29 OCTOBER 2013

Controlling malaria is a war being waged on many fronts. Mosquito nets and coils repel mosquitoes from their human feast; vaccines protect us from the inside and environmental measures clear the stagnant water where mosquitoes like to breed.

Published by The Conversation, October 29, 2013

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