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We are now part of City St George's, University of London. This website contains information relating to our Tooting campus. Please visit our new website to learn more about what we offer across all our campuses.

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Our vision

To establish City St George's, University of London and St George's Hospital as a world leader in genomic medicine.

Our mission

Our mission is to foster collaborations between science and healthcare to:

  • deliver better healthcare for patients
  • conduct cutting edge research
  • train the genomics workforce of the future.

What we do

Click the items below to learn more about what the Genomics Clinical Academic Group (G CAG) does.

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Research

We hold cross-institutional mini-symposiums to raise awareness of the research already happening at City St George’s, which covers a wide range of topics with researchers from a range of different research sections in the City St George's Institutes.

The G CAG has links with many departments at City St George's, particularly the Neuroscience and Cell Biology Research Institute and the Cardiovascular and Genomics Research Institute where researchers are studying various themes such as cardiovascular and neurosciences with many researchers linking to our genetics and genomics research groups.

Education and training

We have an excellent portfolio of education and training opportunities designed to address a range of topics and levels of experience.

The Genomic Medicine programme is a suite of modules designed to upskill and educate in the application of genomics across healthcare.  It is possible to take individual modules for continuing professional development (CPD) purposes or complete a full academic award (PGCert, PGDip, MSc).   Our flagship blended-learning programme is comprised of 13 modules:

  • Fundamentals of human genetics and genomics
  • Omics techniques and technologies
  • Bioinformatics, quality assurance and data interpretation
  • Advanced bioinformatics
  • Genomics of common and rare inherited disease
  • Application of genomics in infectious disease
  • Molecular pathology of cancer and application in diagnosis, screening and treatment
  • Pharmacogenomics and stratified healthcare
  • Genomics of neurological disorders
  • Genomics of cardiovascular disorders
  • Ethical, legal and social issues in applied genomics
  • Introduction to counselling skills in genomics
  • Fetal genomics

Each module is delivered in a block of 5 days of primarily face-to-face learning either at the Tooting Campus of City St George's or at our partners King's College London.  NHS staff may benefit from full-fee funding from NHS England.

New for 2025 is our fully online PgCert Genomic Medicine which is comprised of three core modules (Fundamentals of human genetics and genomics; Genomics of common and rare inherited disease; and Variant interpretation) alongside a fourth module chosen from either Genomics of neurological disorders or Genomics of cardiovascular disorders.  Each module will run across a 10-week period with students able to complete learning when it suits them best.  It is also possible to complete individual modules.

The G CAG has also been involved in developing a range of shorter courses most of which are fully online. We have a set of cutting-edge massive online open courses (MOOCs) available through the Future Learn platform, all of which can be accessed free of charge.  These MOOCs are:

These can be completed across two to five weeks in your own time, being fully self-directed.

There are also two short courses led by expert members of the G-CAG and including highly interactive sessions.  The first is aimed at Oncologists and the second at a more general audience of clinical and healthcare professionals:

Watch this space as we look to develop more education and training for those involved and interested in genomics!

Clinical genomics

The Clinical Genetics service covers a population of 4 million in South West London, Surrey and West Sussex. A multidisciplinary team of doctors, genetic counsellors, specialist nurses and clinical scientists provide support to children and adults affected by or at risk of genetic disorders. The department is a lead training centre for specialist registrars, genetic counsellors, and clinical scientists. 

Across St George’s Hospital several highly specialised disease specific genetic services have been established including:

St George’s clinical teams are active members of seven Rare Disease Collaborative Networks. We work closely with the South East Genomic Medicine Service Alliance for which Dr Frances Elmslie is Clinical Director.

Events and news
Genomics Clinical Academic Group seminar series dates 2025

These meetings take place on Mondays from 12:00 to 13:00 in Lecture Theatre A, B or C and online.

Genomics Clinical Academic Group dates 2025
 Date Speaker Institute TitleRoom 
 27 January Roddy Walsh  Exp. Cardio, CGRI, City St George's  Towards more complex genetic aetiologies for cardiomyopathies  Lecture Theatre A
 10 February  Martin Bird  Exp. Cardio, CGRI, City St George's  Coding and non-coding variation in familial hypercholesterolemia  Lecture Theatre C
 17 March  Rezbieara Rahman Neuro, NCBRI, City St George's   Investigating underexplored areas of myotonic dystrophy: genetic, clinical and diagnostic insights  Lecture Theatre A
 12 May  Francesca Morgante  NCBRI, City St George's  Genetics of dystonia  Lecture Theatre A
 23 June  Sarah Dobbins  Genomics, CGRI, City St George's  Genetics of lymphoedema/lipoedema  Lecture Theatre A
 21 July  Susan Walker Genomics England   Increasing the diagnostic yield of genome sequencing for families with rare disorders through diagnostic discovery  Lecture Theatre A
 15 September  Judith Breuer UCL   Metagenomics in CNS infections  Lecture Theatre A
 29 September  Gred Findlay  The Crick Institute  Saturation genome editing to guide clinical interpretation of variants of uncertain significance To be confirmed
 20 October  To be confirmed To be confirmed  To be confirmed  Lecture Theatre A
 17 November  Clare Turnbull  Institute of Cancer Research  To be confirmed  Lecture Theatre A
 15 December  To be confirmed  To be confirmed  To be confirmed  Lecture Theatre A
Rare Disease Day

On 28 February 2025 City St George's academics, clinicians, charities and patients groups came together to mark Rare Disease Day. Read more about this event.

Who we are

The G-CAG is led by a Director, Dr Emma Matthews, supported by an administrator and a 15-member Steering Committee (details below) which meets quarterly to set key priorities and monitor performance.

Name, job title and email address for steering committee members
 Name Job title Email address
 Alan Pittman  Bioinformatician (also I&I), Senior Lecturer in Computational Genetics  apittman@citystgeorges.ac.uk
 Bethan Frugtniet  Clinical Scientists, St George's Genomics Service  bethan.frugtniet@stgeorges.nhs.uk
 Dan Osborn  Senior Lecturer  dosborn@citystgeorges.ac.uk
 Emma Matthews  G CAG Director, Academic Neurologist  ematthew@citystgeorges.ac.uk
 Esther Dempsey  CRTF, Training Representative  edempsey@citystgeorges.ac.uk
 Frances Elmslie  Genomics Board  frances.elmslie@nhs.net
 Kate Everett  Reader, Genomics Postgraduate and Undergraduate Course Director  keverett@citystgeorges.ac.uk
 Meriel McEntagart  NHS (Clinical Genetics) and GEL  meriel.mcentagart@nhs.net
 Nayana Lahiri  NHS Clinical Genetics Care Group Lead  nayana.lahiri@stgeorges.nhs.net, nlahiri@citystgeorges.ac.uk
Nidhi Sofat Training Programme (GAT) nsofat@citystgeorges.ac.uk
 Pia Ostergaard  Genomics Research Centre  posterga@citystgeorges.ac.uk
 Sahar Mansour  Professor/NHS Consultant  smansour@citystgeorges.ac.uk
 Christopher Carroll  Lecturer  ccarroll@citystgeorges.ac.uk
 Silvia Almedina  Lecturer  snartina@citystgeorges.ac.uk
 Luigi D'Argenzio  Consultant Paediatric Neurologist  luigi.dargenzio@stgeorges.nhs.uk

The Genomics CAG also present regular joint and mini symposiums to highlight developments within their field.

To enquire about becoming a member of the G CAG, please email Vicky Vaghjiani.

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