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Professor Derek Gordon Cook

Professor of Epidemiology
Derek Cook heads the Primary Care Epidemiology Group within the Population Health Research Centre

My background was in Mathematics and Statistics before joining the British Regional Heart Study in 1979 based at The Roal Free School of Medicine within The University of London.  From 1979 I worked with Professor Gerry Shaper on the BRHS for 12 years, becoming a co-director of the study in 1987 and being promoted to Senior Lecturer in Medical Statistics in 1989.  During that time I completed a PhD in Epidemiology and developed interests in cardiovascular & respiratory epidemiology as well as social inequalities in health and health care.  In 1991 I moved to St George's as Senior Lecturer in Epidemiology, subsequently being promoted to Reader and Professor.

My research is focused on 4 areas: (i) the use of large primary care databases for epidemiological and health service research; (ii) the early origins of cardiovascular, metabolic and respiratory diseases; (ii) ethnic differences in cardiovascular diseases and diabetes; (iv) the application of systematic reviewing and meta-analysis within observational epidemiology; specifically within area (ii) above.  

In 1998, I formed the Primary Care Epidemiology Group to bring together and develop expertise on linking and analysis of information from large routine data sets at a time when computerisation of primary care and changes in the NHS were making possible new perspectives on health care and ways of carrying out epidemiological and health services research.  The PCEG includes programmers, statisticians, epidemiologists and general practitioners. 

**1 Pocock SJ, Shaper AG, Cook DG, Packham RF, Lacey RF, Powell P, Russell PF. British Regional Heart Study:- geographic variations in cardiovascular mortality and the role of water quality. Br Med J 1980;280:1243-1249.

**2 Smith AFM, Cook DG. Straight lines with a change-point: a Bayesian analysis of some renal transplant data. Applied Statistics 1980;29:180-189.

*3 Epstein O, Jain S, Lee RG, Cook DG, Boss AM, Scheuer PJ, Sherlock S. D-penicillamine treatment improves survival in primary billiary cirrhosis. Lancet 1981;i:1275-1277.

**4 Pocock SJ, Cook DG, Beresford SAA. Regression of area mortality on explanatory variables: what weighting is appropriate? Applied Statistics 1981;30:286-295.

*5 Cook DG, Cummins RO, Bartley MJ, Shaper AG. Health of unemployed middle-aged men in Great Britain. Lancet 1982;i:1290-1294.

 6 Cummins RO, Cook DG, Hume RC, Shaper AG. Tranquillizer use in middle-aged British men: associations with physical illness, cigarette smoking and alcohol consumption. J Royal College of General Pract 1982;32:745-752.

 7 Pocock SJ, Cook DG, Shaper AG. Analysing geographic variations in cardiovascular mortality: methods and results (with discussion). J R Statist Soc A 1982;145:313-341..

 8 Burney PGJ, Cook DG. Mothers' intentions and the immunizations of their infants. Journal Royal College of General Pract 1983;33:229-232.

*9 Cook DG, Pocock SJ. Multiple regression in geographical mortality studies with allowance for spatially correlated errors. Biometrics 1983;39:361-371.

**10 Shaper AG, Cook DG, Walker M, Macfarlane PW. Prevalence of Ischaemic Heart Disease in middle-aged British men. Br Heart J 1984;51:595-605.

11 Shaper AG, Cook DG, Walker M, Macfarlane PW. Recall of diagnosis by men with ischaemic heart disease. Br Heart J 1984;51:606-611.

12 Bland JM, Jones DR, Bennett S, Cook DG, Haines AP, Macfarlane AJ. Is the clinical trial evidence about new drugs statistically adequate? Br J Clin Pharmacol 1985;19:155-160.

13 Cook DG. Unemployment and health during a recession. The Practitioner 1985;229:559-562.

14 Cook DG. A critical view of the unemployment and health debate. The Statistician 1985;34:73-82.

*15 Cook DG, Shaper AG, Thelle DS, Whitehead TP. Serum uric acid, serum glucose and diabetes: relationships in a population study. Postgrad Med J 1986;62:1001-1006.

16 Cook DG. Can we detect an effect of unemployment on cardiovascular morbidity or mortality? Postgrad Med J 1986;62:801-804.

*17 Cook DG, Shaper AG, Pocock SJ, Kussick SJ. Giving up smoking and the risk of heart attacks: a report from the British Regional Heart Study. Lancet 1986;ii:1376-1380.

18 Johnston DW, Cook DG, Shaper AG. Type A behaviour and ischaemic heart disease in middle-aged British men. Br Med J 1987;295:86-89.

***19 Pocock SJ, Shaper AG, Cook DG, Phillips AN , Walker M. Social class differences in ischaemic heart disease in British men. Lancet 1987;ii:197-201..

*20 Walker M, Shaper AG, Cook DG. Non-participation and mortality in a prospective study of cardiovascular disease. J Epidemiol Community Health 1987;295-299.

21 Cook DG. Respiratory function, smoking and coronary heart disease in British men. Ph.D. London: University of London, 1988;

*22 Cook DG, Shaper AG. Breathlessness, lung function and risk of heart attack. Eur Heart J 1988;9:1215-1222.

**23 Spiteri MA, Cook DG, Clarke SW. The reliability of physical signs in the examination of the chest. Lancet 1988;i:873-875.

24 Whincup PH, Cook DG, Shaper AG, Macfarlane DJ, Walker M. Blood pressure in British children: associations with adult blood pressure and cardiovascular mortality. Lancet 1988;ii:890-893.

25 Cook DG, Shaper AG. Breathlessness, angina pectoris and risk of coronary artery disease. Am J Cardiol 1989;63:921-924.

**26 Cook DG, Shaper AG, Macfarlane P. Using the WHO (Rose) angina questionnaire in cardiovascular epidemiology. Int J Epidemiol 1989;18:607-613. (doi:10.1093/ije/18.3.607)

27 Taylor RG, Maclagan J, Cook DG. Bronchodilator action of inhaled fenoterol and ipratropium in normal subjects: a teaching exercise for medical students. Br J Clin Pharmacol 1989;28:709-713.

*28 Walker M, Shaper AG, Phillips AN, Cook DG. Short stature, lung function and risk of heart attack. Int J Epidemiol 1989;18:602-606. (doi:10.1093/ije/18.3.602)

***29 Webster A, Lee CA, Cook DG, Grundy JE, Emery VC, Kernoff PBA, Griffiths PD. Cytomegalovirus infection increases the progression towards AIDS in a cohort of haemophiliacs infected with human immunodeficiency virus. Lancet 1989;ii:63-66.

**30 Whincup PH, Cook DG, Shaper AG. Early influences on blood pressure a study of 5-7 year-old children. Br Med J 1989;299:587-591.

31 Whincup PH, Cook DG, Shaper AG. Blood pressure measurement in children: the importance of cuff bladder size. J Hypertens 1989;7:845-850.

32 Bruce NG, Cook DG, Shaper AG, Thompson A. Geographical variations in blood pressure in British men and women. J Clin Epidemiol 1990;43:385-393.

33 Bruce NG, Cook DG, Shaper AG. Differences between observers in blood pressure measurement when using an automatic oscillometric recorder. J Hypertens 1990;8(suppl 4):S11-S13.

34 Bruce NG, Cook DG, Shaper AG, Ratcliffe JG. Casual urine concentrations of sodium, potassium and creatinine in population studies of blood pressure. J Hum Hypertens 1990;4:597-602.

35 Cook DG, Kussick SJ, Shaper AG. The respiratory benefits of stopping smoking. Journal of Smoking-Related Disorders 1990;1:45-58.

36 Cook DG, Morris JK, Shaper AG, Walker M. Consultation rates among middle aged men in general practice over three years. Br Med J 1990;301:647-650.

*37 Whincup PH, Cook DG, Phillips AN, Shaper AG. ABO blood group and ischaemic heart disease in British men. Br Med J 1990;300:1679-1682.

38 Morris JK, Cook DG. A critical review of the effect of factory closures on health. Br J Ind Med 1991;48:1-8.

39 Bruce NG, Cook DG, Shaper AG, Ratcliffe JG, Thomson AG. Casual urine concentrations of sodium and potassium and geographic blood pressure variations in Great Britain. J Hum Hypertens 1992;6:157-164.

40 Morris JK, Cook DG, Walker M, Shaper AG. Non-consulters and high consulters in general practice; cardio-respiratory health and risk factors. J Public Health Med 1992;14:131-137.

*41 Morris JK, Cook DG, Shaper AG. Non-employment and changes in smoking, drinking and body weight. Br Med J 1992;304:536-541.

*42 Phillips AN, Neaton JD, Cook DG, Grimm RH, Shaper AG. Leukocyte count and risk of major coronary heart disease events. Am J Epidemiol 1992;136:59-70.

43 Phillips AN, Neaton JD, Cook DG, Grimm RH, Shaper AG. The leukocyte count and risk of lung cancer. Cancer 1992;69:680-684.

44 Tang JL, Cook DG, Shaper AG. Giving up smoking: how rapidly does the excess risk of ischaemic heart disease dissapear? Journal of Smoking-Related Disorders 1992;3:203-216.

*45 Whincup PH, Cook DG, Papacosta O. Do maternal and intrauterine factors influence blood pressure in childhood? Arch Dis Child 1992;67:1423-1429.

46 Whincup PH, Cook DG, Papacosta O, Walker M. Childhood blood pressure, body build and birthweight: geographic associations with cardiovascular mortality. J Epidemiol Community Health 1992;46:396-402.

*47 Whincup PH, Bruce NG, Cook DG, Shaper AG. The Dinamap 1846SX automated blood pressure recorder: comparison with the Hawksley random zero sphygnomanometer under field study conditions. J Epidemiol Community Health 1992;46:164-169.

48 Roy DM, Brenner MK, Cook D, Duncan RI, Griffiths PD, Grundy JE. Transfer of humoral immunity against cytomegalovirus proteins following transplantation of T-cell-depleted allogenic bone marrow from seropositive donors. J Med Virology 1993;41:150-8.

*49 Cook DG, Whincup PH, Papacosta O, Strachan DP, Jarvis MJ, Bryant A. Relation of passive smoking as assessed by salivary cotinine concentration and questionnaire to spirometric indices in children. Thorax 1993;48:14-20. (doi:10.1136/thx.48.1.14)

50 Whincup PH, Cook DG, Strachan DP, Papacosta O. Time trends in respiratory symptoms in childhood over a 24 year period. Arch Dis Child 1993;68:729-734.

**51 Cook DG, Whincup PH, Jarvis MJ, Strachan DP, Papacosta O, Bryant A. Passive exposure to tobacco smoke in children aged 5-7: individual, family and community factors. Br Med J 1994;308:384-9

52 Whincup P, Cook D, Papacosta O, Walker M, Perry I. Maternal factors and development of cardiovascular risk: evidence from a study of blood pressure in children. J Hum Hypertens 1994;8:337-343.

53 Strachan DP, Seagroatt V, Cook DG. Chest illness in infancy and chronic respiratory disease in later life: an analysis by month of birth. Int J Epidemiol 1994;23:1060-1068. (doi:10.1093/ije/23.5.1060)

*54 Majeed FA, Cook DG, Anderson HR, Hilton S, Bunn S, Stones C. Using patient and general practice characteristics to explain variations in cervical smear rates. Br Med J 1994;308:1272-1276.

**55 Morris JK, Cook DG, Shaper AG. Loss of Employment and Mortality. Br Med J 1994;308:1135-1139.

*56 Tobias JH, Cook DG, Chambers TJ, Dalzell N. A comparison of bone mineral density between Caucasian, Asian and Afro-caribbean women. Clinical Science 1994;87:587-591.

57 Majeed FA, Cook DG, Poloniecki J, Griffiths J, Stones C. Sociodemographic variables for general practices: use of census data. Br Med J 1995;310:1373-1374.

58 Majeed FA, Cook DG, Hilton S, Poloniecki J, Hagen A. Annual night visiting rates in 129 general practices in one family health services authority: association with patient and general practice charateristics. Br J Gen Pract 1995;45:531-535.

59 Majeed FA, Cook DG, Given-Wilson R, Vecchi P, Poloniecki J. Do General Practitioners influence the uptake of breast cancer screening? J Med Screening 1995;2:119-124.

60 Majeed FA, Cook DG, Poloniecki J, Martin D. Using data from the 1991 census. Br Med J 1995;310:1511-1514.

**61 Whincup P, Cook D, Papacosta O, Walker M. Birthweight and blood pressure: cross-sectional and longitudinal relationship in childhood. Br Med J 1995;311:773-776.

62 Majeed FA, Cook DG. Age and sex differences in the management of ischaemic heart disease. Public Health 1996;110:7-12.

63 Aylin P, Majeed FA, Cook DG. Home visiting by general practitioners in England and Wales. Br Med J 1996;313:207-210.

64 Majeed A, Cook D, Evans E. Variations in general practice prescribing costs - implications for setting and monitoring prescribing budgets. Health Trends 1996;28:52-55.

*65 Montgomery SM, Bartley MJ, Cook DG, Wadsworth MEJ. Health and social precursors of unemployment in young men. J Epidemiol Community Health 1996;50:415-422.

66 Whincup PH, Cook DG, Adshead F, et al. Cardiovascular risk factors in British children in towns with widely differing cardiovascular mortality. Br Med J 1996;313:79-84.

*67 Cook DG, Peacock JL, Feyerabend C, et al. Relation of caffeine intake and blood caffeine levels during pregnancy to intrauterine growth. Br Med J 1996;313:358-362

*68 Taylor SJC, Whincup PH, Cook DG, Papacosta O, Walker M. Size at birth and blood pressure: a cross-sectional study in 8-11 year old children. Br Med J 1997;314:475-480

**69 Whincup PH, Cook DG, Adshead F, Taylor S, Walker M, Alberti KGMM. Childhood size is more strongly related than size at birth to glucose and insulin levels in 10-11 year old children. Diabetologia 1997;40:319-326

**70 Cook DG, Carey IM, Whincup PH, Papacosta O, Chirico S, Bruckdorfer KR, Walker M. Effects of fresh fruit consumption on lung function and wheeze in children. Thorax 1997;52:628-633.

**71 Leeson CPM, Whincup PH, Cook DG, Donald AE, Lucas A, Deanfield JE. Flow-mediated dilatation in 9- to 11- year old children: the influence on intrauterine and childhood factors. Circulation 1997;96:2233-8

***72 Strachan DP, Cook DG. Health effects of passive smoking – 1. Parental smoking and lower respiratory illness in infancy and early childhood. Thorax 1997;52:905-14.

**73 Anderson HR, Cook DG. Health effects of passive smoking – 2. Passive smoking and sudden infant death syndrome.  Review of the epidemiological evidence. Thorax 1997;52:

***74 Cook DG, Strachan DP. Health effects of passive smoking – 3. Parental smoking and prevalence of respiratory symptoms and asthma in school age children. Thorax 1997;52:1081-1094

***75 Cappuccio FP, Cook DG, Atkinson R, Strazzullo P. Prevalence, detection and management of cardiovascular risk factors in different ethnic groups in South London. Heart 1997;78:555-563

**76 Strachan DP, Cook DG. Health effects of passive smoking – 5.  Parental smoking and allergic sensitisation in children. Thorax 1998;53:117-123

*77 Strachan DP, Cook DG. Health effects of passive smoking – 4. Parental smoking, middle ear disease and adenotonsillectomy in children. Thorax 1998;53:50-56

****78 Strachan DP, Cook DG. Health effects of passive smoking – 6.  Parental smoking and childhood asthma: longitudinal and case-control studies. Thorax 1998;53:204-212

*79 Montgomery SM, Cook DG, Bartley MJ, Wadsworth MEJ. Unemployment and its relationship to cigarette smoking, alcohol consumption and body mass index in young men. Eur J Public Health 1998;8:21-27

*80 Peacock JL, Cook DG, Carey I, et al. Maternal cotinine levels during pregnancy and birth-weight-for-gestational-age. Int J Epidemiol 1998;27:647-656. (doi:10.1093/ije/27.4.647)

*81 Cook DG, Strachan DP. Passive smoking – 7. Parental smoking and bronchial reactivity and peak flow variability in children. Thorax 1998;53:295-301

**82 Baker EH, Dong Y, Sagnella G,Rothwell M, Onipinla A, Markandu ND, Cappuccio FP, Cook DG, Carter N, Persu A, Corvol P, Jeunemaitre X, MacGregor GA.  Association of hypertension with T594M  mutation in the beta subunit of the epithelial sodium channel in black people resident in London. Lancet 1998;351:1388-92

*83 Carey IM, Strachan DP, Cook DG. The effects of changes in fresh fruit consumption on ventilatory function in healthy British adults. Am J Respir Crit Care Med  1998;158:728-733.

**84 Cook DG, Strachan DP, Carey IC. Passive smoking – 9: Parental smoking and spirometric indices in children. Thorax 1998;53:884-893.

85 Cappuccio FP, Cook DG, Atkinson RW, Wicks PD. The Wandsworth Heart & Stroke Study: a population based survey of cardiovascular risk factors in different ethnic groups.  Nutr Metab Cardiovasc Dis  1998;8:371-85.

****86 Cook DG, Strachan DP. Health effects of passive smoking -10: Summary of effects of parental smoking on children’s respiratory health and implications for research. Thorax 1999;54:357-366.

*87 Montgomery SM, Cook DG, Bartley MJ, Wadsworth MEJ. Unemployment predates symptoms of depression and anxiety resulting in medical consultation in young men. Int J Epidemiol 1999;28:95-100.

88 Ness AN, Cappuccio FP, Atkinson R, Khaw K, Cook DG. Plasma vitamin C in people of African descent, South Asian Origin and Caucasians. Int J Epidemiol 1999;28:450-5.

89 Carey IM, Cook DG, Strachan DP. The effects of passive smoke exposure assessed by questionnaire and salivary cotinine on lung function in a longitudinal study of adults. Epidemiology 1999;10:319-26.

*90 Sagnella GA, Rothwell MW, Onipinla AK, Wicks PD, Cook DG, Cappuccio FP. A population study of ethnic variations in the angiotensin converting enzyme I/D polymorhpism: relationships with gender, hypertension and impaired glucose metabolism.J Hypertens 1999;17:657-64

*91 Reid F, Cook DG, Majeed FA. Explaining variation in hospital admission rates between general practices: cross sectional study. BMJ 1999;319:98-103.

92 Cook DG, Whincup PH, Miller G, Carey IM, Adshead FJ, Papacosta O, Walker M, Howarth  D. Fibrinogen and factor VII levels are related to obesity but not to fetal growth or social class in children aged 10-11 years.  Am J Epidemiol 1999;150:727-36

93 Carey IM, Cook DG, Strachan DP. The effects of adiposity and weight change on forced expiratory volume decline in a longitudinal study of adults. Int J Obesity and Related Metabolic Disorders 1999;23:979-85

94 Harris TJ, Cook DG, Wicks PD, Cappuccio FP. Ethnic differences in use of hormone replacement therapy: community based survey. BMJ 1999;319:610-1

**95 Dong Y, Zhu H, Sagnella GA, Carter ND, Cook DG, Cappuccio FP. Association between the C825T polymorphism of the G-protein b3 subunit gene and hypertension in blacks.  Hypertension 1999;34:1193-6

96 Hall S, Talmud PJ, Cook DG, Wicks PD, Rothwell MW, Strazullo P, Sagnella GA, Cappuccio FP. Frequency of allelic association of common variants in the lipoprotein lipase gene in different ethnic groups: The Wandsworth Heart and Stroke Study. Genetic Epidemiology 2000;18:203-16.

***97 Cook DG, Mendall MA, Whincup PH, Carey IM, Ballam L, Morris JE, Miller GJ, Strachan DP.  C reactive protein concentration in children: relationship to adiposity and other cardiovascular risk factors. Atherosclerosis 2000;149:139-50

*98 Leeson CPM, Whincup PH, Cook DG, Mullen MJ, Donald AE, Seymour CA, Deanfield JE. Cholesterol and distensibility in the first decade of life: a population based study. Circulation 2000;101:1533-8

99 Ballam LD, Mendall MA, Asante M, Morris J, Strachan DP, Whincup PH, Cook DG. Western blotting is useful in the salivary diagnosis of H. pylori infection. J Clin Pathol  2000;53:314-7

*100 Jarvis MJ, Goddard E, Higgins V, Feyerabend C, Bryant A, Cook DG. Children’s exposure to passive smoking in England since the 1980s: cotinine evidence from population surveys. BMJ 2000;321:343-5

101 Harris E, Cook DG, Wicks P, Cappuccio FP. Impact of the new American Diabetes Association and World Health Organisation diagnostic criteria for diabetes on subjects from three ethnic groups living in the UK. Nutr Metab Cardiov Dis 2000;10:305-9

**102 Taylor SJC, Whincup PH, Hindmarsh PC, Lampe F, Odoki K, Cook DG. Performance of a new pubertal self-assessment questionnaire: a preliminary study. Paediatric and Perinatal Epidemiology 2001;15:88-94

103 Cook DG, Cappuccio FP, Atkinson RW, Wicks PD, Chitolie A, Nakandakare ER, Sagnella GA, Humphries SE. Ethnic differences in fibrinogen levels: the role of environmental factors and the beta-fibrinogen gene. Am J Epidemiol 2001;153:799-806

104 Shah S, Harris TJ, Cook DG. Differences in hormone replacement therapy use by social class, region and psychological symptoms. Br J Obstet Gynaecol 2001;108:269-75

105 Cappuccio FP, Duneclift S, Atkinson RW, Cook DG. Use of alternative medicines in a multi-ethnic population. Ethnicity & Disease 2001;11:11-18

106 Shah S, Harris TJ, Rink E, DeWilde S, Victor C, Cook DG. Do income questions and seeking consent to link medical records reduce response rates? A randomised controlled trial among older people. Br J Gen Pract 2001;51:223-5

107 Waterworth DM, Talmud PJ, Humphries SE, Wicks PD, Sagnella GA, Strazullo P, Alberti KGMM, Cook DG, Cappuccio FP.  Variable effects of the ApoCIII C-482T variant on insulin, glucose and triglyceride concentrations in different ethnic groups. Diabetologia 2001; 44:245-8

108 Blackwood AM, Cappuccio FP, Cook DG, Sagnella GA.  Urinary calcium excretion, sodium intake and blood pressure in a multi-ethnic population: results of the Wandsworth Heart & Stroke Study. J Hum Hypert 2001;15:229-37

*109 Whincup PH, Gilg J, Odoki K, Taylor SJC, Cook DG. Age of menarche in contemporary British teenagers: survey of girls born between 1982 and 1986. BMJ 2001;322:1095-6

110 Dong Y.B., Zhu H, Baker EH, Sagnella GA, MacGregor GA, Carter,ND, Wicks PD, Cook DG, Cappuccio FP. T594M and G442V polymorphisms of the sodium channel beta subunit and hypertension in a black population.  J Hum Hypert 2001;15:425-30.

111 De Wilde S, Carey IM, Richards N, Hilton S, Cook DG. Do children who become autistic consult more often after MMR vaccination? Br J Gen  Pract 2001;51:226-7

112 Shah S, Cook DG. Inequalities in the treatment and control of hypertension: age, social isolation and lifestyle are more important than economic circumstances. J Hypert 2001;19:1333-40

113 Davey G, Cook D, McKeigue P. A rebuttal - the RsaI polymorphism in the a-fibrinogen gene and response of plasma fibrinogen to physical training.  Thromb Haemost 2001;85:188.

114 Victor C, Scambler S, Shah S, Cook DG, Harris T, Rink E, De Wilde S.  Has loneliness amongst older people increased? An investigation into variations between cohorts. Ageing and Society 2002;22:585-97.

**115 Whincup PH, Gilg J, Papacosta O, Seymour C, Miller G, Alberti KGMM, Cook DG. Early evidence of ethnic differences in cardiovascular risk: a comparison of South Asian and European children. BMJ 2002;324:635-8

*116 Reid FDA, Whincup PH, Cook DG. Use of statins in the secondary prevention of CHD: are there inequalities? Br Heart J 2002;88:15-19

117 Cappuccio FP, Bell R, Perry IJ, Gilg J, Ueland PM, Refsum H, Sagnella GA, Jeffery S, Cook DG. Homocystine levels in men and women of different ethnic and cultural background living in England. Atherosclerosis 2002;164:95-102.

118 Court C, Cook DG, Strachan DP. The descriptive epidemiology of house dust mite specific and total IgE in England using a nationally representative sample. Clinical & Experimental Allergy 2002;32:1033-41.

119 Harris TJ, Cook DG, Shah S, Victor CR, DeWilde S, Beighton C. Mammography uptake predictors in older women. Family Practice 2002;19:661-4

**120 Owen CG, Whincup PH, Odoki K, Gilg J, Cook DG. Infant feeding and blood cholesterol; a study in adolescents and a systematic review. Pediatrics 2002;110:597-608

121 Court C, Cook DG, Strachan DP. Comparative epidemiology of atopic and non-atopic wheeze and diagnosed asthma in a national study of English adults. Thorax 2002;57:951-7 (doi:10.1136/thorax.57.11.951)

*122 Owen CG, Whincup PH, Odoki K, Gilg J, Cook DG. Birthweight and blood cholesterol level: study in adolescence and systematic review. Pediatrics 2003;111:1081-9.

**123 DeWilde S, Carey IM, Bremner SA, Richards N, Hilton SR, Cook DG. Evolution of statin prescribing 1994-2001: a case of agism but not of sexism? Heart 2003;89:417-21

124 Harris T, Cook DG, Victor C, Rink E, Mann AH, Shah S, DeWilde S, Beighton C.  Predictors of depressive symptoms in older people – a survey of two general practice populations. Age & Aging 2003;32:510-8

125 Miller MA, Sagnella GA, Kerry SM, Strazullo P, Cook DG, Cappuccio FP. Ethnic differences in circulating soluble adhesion molecules: the Wandsworth Heart and Stroke Study. Clinical Science 2003;104:591-8

126 Bremner SA, Carey IM, DeWilde S, Richards N, Maier WC, Hilton SR, Strachan DP, Cook DG. Early life exposure to antibacterials and the subsequent development of hay-fever. Clinical & Experimental Allergy 2003;33:1518-25

*127 Owen CG, Whincup PH, Gilg J, Cook DG. Effect of breast feeding in infancy on blood pressure in later life: systematic review and meta-analysis. BMJ 2003;327:1189-92

128 Carey IM, Cook DG, DeWilde S, Bremner S, Richards N, Caine S, Strachan DP, Hilton SR.  Implications of the problem orientated medical record (POMR) for research using electronic GP databases: a comparison of the Doctors Independent Network Database (DIN) and the General Practice Research Database (GPRD). BMC Family Practice 2003;4:14 (http://www.biomedcentral.com/1471-2296/4/14)

129 Barbato A, Cappuccio FP, Folkerd EJ, Strazzullo P, Sampson B, Cook DG, Alberti KGMM. Metabolic Syndrome and Renal Sodium Handling in 3 ethnic groups living in England. Diabetalogia 2004;47:40-6

130 Miller MA, Kerry SM, Cook DG, Cappuccio FP. Cellular adhesion molecules and blood pressure: interaction with sex in a multi-ethnic population. J Hypertension 2004;22:705-11

131 Carey IM, Cook DG, De Wilde S, Bremner SA, Richards N, Caine S, Strachan DP, Hilton SR.  Developing a large electronic primary care database (Doctors’ Independent Network) for research. Int J Med Inform 2004;73:443-53

132 DeWilde S,  Carey IM, Bremner SA, Richards N, Strachan DP, Hilton SR, Cook DG.  A comparison of the recording of 30 common childhood conditions in the Doctors’ Independent Network and General Practice Research Databases. Health Statistics Quarterly 2004;22:21-30

**133 Whincup PH, Gilg J, Emberson J, Jarvis MJ, Walker M, Cook DG. Passive smoking and risk of coronary heart disease and stroke: prospective study with cotinine measurement. BMJ 2004;329:200-4

134 Harris T, Cook DG, Victor CR, Mann A, DeWilde S, Carey IM.  Linking survey data with computerised medical records to predict consulting by older people. Brit J Gen Pract 2004;54:928-31

*135 Huxley R, Owen C, Whincup PH, Cook DG, Colman S, Collins R.  Birthweight and subsequent cholesterol levels:exploration of the “Fetal Origins” hypothesis. JAMA 2004;292:2755-64

136 Bremner SA, Carey IM, DeWilde S, Richards N, Maier WC, Hilton SR, Strachan DP, Cook DG. Timing of routine immunisations and subsequent hay fever risk. Arch Dis Child 2005;90:567-73 (Article available from: http://adc.bmjjournals.com/cgi/full/90/6/567)

*****137 Owen C, Martin RM, Whincup PH, Smith GD, Cook DG.  Effect of infant feeding on the risk of obesity across the life course: a quantitative review of published evidence. Pediatrics 2005;115:1367-77

138 Harris TJ, Cook DG, Victor CR, DeWilde S, Carey IM. Linking questionnaires to primary care records: factors affecting consent in older people? J Epidemiol Community Health 2005;59:336-8

139 Whincup PH, Gilg J, Owen CG, Odoki K, Alberti KGMM, Cook DG. British South Asians aged 13-16 years have higher fasting glucose and insulin levels than Europeans. Diabet Med 2005;22:1275-7

140 Harris T, Cook DG, Victor CR, Rink P, Beighton C, DeWilde S, Carey IM.  Are depression, anxiety and health beliefs important factors for predicting older peoples’ primary care consulting?  Age & Ageing 2005;34:398-401

141 Owen CG, Whincup PH, Cook DG. Are early life factors responsible for international differences in adult blood pressure? Int J Epidemiol 2005;34:649-54

**142 De Lusignan S, Sismanidis C, Carey IM, DeWilde S, Richards N, Cook DG. Trends in the prevalence and management of type 2 diabetes 1994-2001. BMC Family Practice 2005;6:13 (Article available from: http://www.biomedcentral.com/1471-2296/6/13 )

143 Miller MA, Kerry SM, Dong Y Sagnella GA, Cook DG, Cappuccio FP. Circulating soluble E-selectin levels and the Ser128Arg polymorphism in individuals from different ethnic groups. Nutr Metab Cardiovasc Dis 2005;15:65-70

*144 Whincup PH, Gilg JA, Donald AE, Katterhorn M, Oliver C, Cook DG, Deanfield JE. Arterial distensibility in adolescents: the influence of obesity, the metabolic syndrome and classical risk factors. Circulation 2005;112:1789-97 (DOI: 10.1161/CIRCULATIONHA.104.5632663)

145 Whincup PH, Owen CO, Sattar N, Cook DG. School dinners and markers of cardiovascular health and type 2 diabetes in 13-16 year olds: cross-sectional study. BMJ 2005;331:1060-1 (DOI: 10.1136/bmj.38618.540729.AE)

146 Huang S, Cook DG, Hinks LJ, Chen XH, Ye S, Gilg JA, Jarvis MJ, Whincup PH, Day INM. CYP2A6 , MAOA, DBH, DRD4 and 5HT2A genotypes, smoking behaviour and cotinine levels in 1518 UK adolescents. Pharmacogenetics and genomics 2005;15:839-50

***147 Owen C, Martin RM, Whincup PH, Smith GD, Gillman MW, Cook DG. The effect of breast feeding on mean BMI throughout life; a quantitative review of published and unpublished observational evidence. Amer J Clin Nutr 2005;82:1298-307

148 Lawlor DA, Owen CG, Davies AA, Whincup PH, Ebrahim S, Cook DG, Smith GD. Sex differences in the association between birth weight and total cholesterol. A meta-analysis. Ann Epidemiol 2006;16:19-25 (DOI: 10.1016/j.annepidem.2005.04.006)

149 Rodriguez S, Huang S, Chen X, Gaunt TR, Sydall HE, Gilg JA, Miller GJ, Cooper CC, Cook DG, Whincup PH, Day INM. A study of TH01 and IGF2-INS-TH haplotypes in relation to smoking initiation in three independent surveys.  Pharmacogenetics and genomics 2006;16:15-23

*150 Harris T, Cook DG, Victor CR, DeWilde S, Beighton C. Onset and persistence of depression in older people – results from a 2-year community follow-up study. Age & Ageing 2006;35:25-32 (DOI: 10.1093/ageing/afi216)

151 Smeeth L, Donnan PT, Cook DG. The use of primary care databases:case-control and case-only designs Family Practice 2006;23:597-604 (DOI: 10.1093/fampra/cml025)

*152 DeWilde S, Carey IM, Emmas C, Richards N, Cook DG. Trends in the prevalence of diagnosed atrial fibrillation, its treatment with anticoagulation and predictors of such treatment in UK primary care. Heart 2006;92:1064-70 (DOI 10.1136/hrt.2005.069492)

153 Owen CG, Carey IM, De Wilde S, Whincup PH, Wormald R, Cook DG. The epidemiology of medical treatment for glaucoma and ocular hypertension in the UK: 1994-2003. Br J Ophthalmol 2006;90:861-8 (DOI: 10.1136/bjo.2005.088666)

**154 Rudnicka AR, Mt-Isa S, Owen CO, Cook DG, Ashby D.  Variations in primary open angle glaucoma prevalence by age, gender and race: a bayesian meta-analysis. Invest Ophth Vis Sci 2006;47:4254-4261 (DOI:10.1167/iovs.06-0299)

**155 Owen CG, Martin RM, Whincup PH, Smith GD, Cook DG. Does breastfeeding influence risk of type 2 diabetes in later life? A quantitative review of published evidence. Amer J Clin Nutr 2006;84:1043-54

156 DeWilde S, Carey IM, Harris T, Richards N, Victor C, Hilton SR, Cook DG. Trends in potentially inappropriate prescribing amongst older, UK primary care patients. Pharmacoepidemiology and Drug Safety 2007;16:658-667 (DOI: 10.1002/pds.1306)

157 Carey IM, DeWilde S, Harris T, Whincup PH, Cook DG. Spurious trends in coronary heart disease incidence: unintended consequences of the new UK GP contract?  BJGP 2007;57:486-9

158 Bremner SA, Carey IM, DeWilde S, Richards N, Maier WC, Hilton SR, Strachan DP, Cook DG. Vaccinations, infections and antibacterials in the first grass pollen season of life and risk of later hay fever. Clin & Exp Allergy 2007;37:512-7

**159 Huxley R, Owen CG, Whincup PH, Cook DG, Rich-Edwards J, Smith GD, Collins R.  Is birthweight a risk factor for coronary heart disease in later life? Am J Clin Nutr 2007;85:1244-50

160 Ussher MH, Owen CO, Cook DG,Whincup PH.  The relationship between physical acivity, sedentary behaviour and psychological wellbeing among adolescents. Social Psychiatry Psychiatr Epidemiol 2007;42:851-6 (DOI:10.1007/s00127-007-0232-x)

161 DeWilde S, Carey IM, Richards N, Whincup PH, Cook DG.  Trends in secondary prevention of ischaemic heart disease in the UK 1994-2005: use of individual and combination treatment. Heart 2008;94:83-8 (DOI:10.1136/hrt.2006.111757)

162 Bremner SA, Carey IM, DeWilde S, Richards N, Maier WC, Hilton SR, Strachan DP, Cook DG. Infections  presenting  for clinical care in early life and  later risk of hay fever in two UK birth cohorts. Allergy 2008;63:274-83 (DOI:10.1111/j.1398-9995.2007.01599.x)

163 Shah SM, Cook DG. Socio-economic determinants of casualty and NHS Direct use. J Pub Health 2008;30:75-81 (DOI: 10.1093/pubmed/fdn001)

164 Harris TJ, Carey IM, Victor CR, Adams R, Cook DG.  Optimising recruitment into a study of physical activity in older people: a randomised controlled trial of different approaches. Age & Ageing 2008;37:659-65 (DOI:10.1093/ageing/afn159)

165 Carey IM, DeWilde S, Harris T, Victor C, Richards N, Hilton SR, Cook DG. What factors predict potentially inappropriate primary care prescribing in older people? Analysis of UK primary care patient record database. Drugs & Ageing 2008;25:693-706

*166 Owen CG, Whincup PH, Kaye SJ, Martin RM, Smith G D, Cook DG for the EARLYREAD collaboration. Does initial breastfeeding lead to lower cholesterol in adult life? A quantitative review of the evidence. AJCN 2008;88:305-14

167 Harris TJ, Victor CR, Carey IM, Adams R, Cook DG.  Less healthy, but more active: opposing selection biases when recruiting older people to a physical activity study through primary care. BMC Public Health 2008;8:182 (DOI: 10:1186/1471-2458-8-182)

168 Shah SM, Carey IM, DeWilde S, Richards N, Cook DG.  Trends and inequities in beta-blocker prescribing for heart failure. BJGP 2008;58:862-9 (DOI:10.3399/bjgp08X376195)

****169 Whincup PH,  Kaye S, Owen CG, Huxley R, Cook DG on behalf of the EARLYREAD collaboration. Birthweight and Risk of Type 2 Diabetes: a Systematic Review. JAMA 2008;300:2886-97 (DOI:10.1001/jama.2008.886)

170 Forbes LJL, Patel MD, Rudnicka AR, Cook DG, Bush T, Stedman JR, Whincup PH, Strachan DP, Anderson HR.  Chronic exposure to outdoor air pollution and markers of systemic inflammation. Epidemiology 2009;20:245-53 (DOI:10.1097/EDE.0b013e318190ea3f)

171 Jefferis BJ, Thomson AG, Lennon LT, Feyerabend C, Doig M, McMeekin L, Wannamethee SG, Cook DG, Whincup PH. Changes in environmental tobacco smoke (ETS) exposure over a 20 year period: cross sectional and longitudinal analyses. Addiction 2009;104:496-503 (DOI:10.1111/j.1360-0443.2008.02473.x)

*172 Harris T, Owen CG, Victor C, Adams R, Ekelund U, Cook DG.  A comparison of questionnaire, accelerometer and pedometer: measures in older people. Med Sci Sports Exer 2009;41:1392-1402

173 Owen CG, Carey IM, DeWilde S, Whincup PH, Wormald R, Cook DG. Persistency with medical treatment for glaucoma and ocular hypertension in the United Kingdom; 1994-2005. Eye 2009 23:1098-1110 (DOI:10.1038/eye.2008.213)

*174 Harris T, Owen CG, Victor CR, Adams R, Cook DG.  What factors are associated with physical activity in older people, assessed objectively by accelerometry? Br J Sports Medicine 2009;43:442-50 (doi:10.1136/bjsm.2008.048033)

175 Carey IM, Nightingale CM, DeWilde S, Harris T, Whincup PH, Cook DG. Blood pressure recording bias during a period when the Quality and Outcomes Framework was introduced. J Human Hypertension 2009 23:764-70 (DOI:10.1038/jhh.2009.18)

176 Forbes LJL, Kapetanakis V, Rudnicka AR, Cook DG, Bush T, Stedman JR, Whincup PH, Strachan DP, Anderson RA.  Chronic exposure to outdoor air pollution and lung function in adults. Thorax 2009;64:657-63 (doi:10.1136/thx.2008.109389)

*177 Owen CG, Nightingale CM, Rudnicka AR, Cook DG, Ekelund U, Whincup PH. Ethnic and gender differences in physical activity levels among 9-10 year old primary school children of white European, South Asian and African-Caribbean origin: the Child Heart Health Study in England (CHASE study). IJE 2009;38:1082-93 (DOI:10.1093/ije/dyp176)

**176 Owen CG, Whincup PH, Orfei L, Chou Q-A, Rudnicka AR, Wathern AK, Kaye SJ, Eriksson JG, Osmond C, Cook DG.  Is  body mass index before middle age related to coronary heart disease in later life?  Evidence from observational studies. IJO 2009;33:866-77 (doi:10.1038/ijo.2009.102)

177 Forbes LJL, Patel MD, Rudnicka AR, Cook DG, Bush T, Stedman JR, Whincup PH, Strachan DP, Anderson RA. Chronic exposure to outdoor air pollution and cardiovascular disease. Environmental Health 2009;8:30: (doi:10.1186/1476-069X-8-30)

178 Jefferis BJ, Lowe GDO, Welsh P, Rumley A, Lawlor DA, Ebrahim S, Carson C, Doig M, Feyerabend C, McMeekin L, Wannamethee SG, Cook DG, Whincup PH. Secondhand smoke (SHS) exposure is associated with circulating markers of inflammation and endothelial function in adult men and women. Atherosclerosis 2010;208:550-6 (doi:10.1016/j.atherosclerosis.2009.07.044)

179 Shah SM, Carey IM, Harris T, DeWilde S, Cook DG.  Calcium supplementation, cardiovascular disease and mortality in older women. Pharmacoepidemiology & Drug Safety 2010;19:59-64 (doi:10.1002/pds.1859)

180 Donin AS, Nightingale CM, Owen CG, Rudnicka AR, MacNamara MC,  Prynne CJ, Stephen AM, Cook DG, Whincup PH.  Nutritional composition of the diets of South Asian, black African-Caribbean and white European children in the United Kingdom: the Child Heart and Health Study England (CHASE). Brit J Nutr 2010;104:276-85 (doi:10.1017/S000711451000070X)

181 Owen CG, Carey IM, Shah S, DeWilde S, Wormald R, Whincup PH, Cook DG. Hypotensive medication, statins, and the risk of glaucoma. IOVS 2010;51:3524-30 (doi:10.1167/iovs.09-4821)

182 Whincup PH, Nightingale CM, Owen CG, Rudnicka AR, Gibb I, McKay CM, Donin AS, Sattar N, Alberti GMM, Cook DG.  Early emergence of ethnic differences in type 2 diabetes precursors in the UK: the Child Heart and Health Study in England (CHASE Study). PLOS Med 2010:7(4):e1000263. (doi:10.1371/journal.pmed.1000263)

183 Owen CG, Nightingale CM, Rudnicka AR, Sattar N, Cook DG, Ekelund U, Whincup PH. Physical activity, obesity and cardiometabolic risk factors in 9-10 year old children of white European, South Asian and black African-Caribbean origin: the Child Heart Health Study in England (CHASE). Diabetalogia 2010 53:1620-30 (DOI: 10.1007/s00125-010-1781-1)

184 Owen CO, Nightingale CM, Rudnicka AR, Ekelund U, McMinn AM, van Sluijs E, Griffin SJ, Cook DG, Whincup PH. Family dog ownership and levels of physical activity in childhood: findings from the Child Heart and Health Study in England. Am J Public Health 2010;100:1669-71 (doi: 10.2105/AJPH.2009.188193)

185 Shah S, Carey IM, Harris T, DeWilde S, Lewis S, Hubbard R, Cook DG.  A novel methodology for identifying care home residents in primary care databases. Age & Aging 2010 39:617-23  (doi: 10.1093/ageing/afq086)

186 Jefferis BJ, Lawlor DA, Ebrahim S, Wannamethee SG, Feyerabend C, Doig M, McMeekin L, Cook DG, Whincup PH. Cotinine assessed secondhand smoke exposure and risk of CVD in older adults. Heart 2010;96:854-9 (doi:10.1136/hrt.2009.191148)

187 Timpson NJ, Forouhi NG, Brion MJ, Harbord RM, Cook DG, Johnson P, McConnachie A, Morris R, Rodriguez S, Luan J,  Ebrahim S, Padmanabhan S, Watt G, Bruchdorfer KR, Wareham N, Whincup PH, Chanock S, Sattar N,  Lawlor DA, Davey Smith G.   Genetic variation at the SLC23A1 locus is associated with circulating levels of L-ascorbic acid (vitamin C).  Evidence from 5 independent studies with a total of 15087 participants.  AJCN 2010;92:375-82 (doi: 10.3945/ajcn.2010.29438)

188 Rudnicka AR, Owen CO, Nightingale CM, Cook DG, Whincup PH. Ethnic differences in the prevalence of myopia and ocular biometry in 10-11 year old children; the CHASE Eye study. Invest Opthalmol Vis Sci 2010;51:6270-6 (doi: 10.1167/iovs.10-5528)

189 Donin AS, Nightingale CM, Owen CG, Rudnicka AR, MacNamara MC,  Prynne CJ, Stephen AM, Cook DG, Whincup PH.  Ethnic differences in blood lipids and dietary intake between UK children of black African, black Caribbean, South Asian, and white European origin: the Child Heart and Health Study in England (CHASE). AJCN 2010;92:776-83 (doi: 10.3945/ajcn.2010.29533)

190 Shah SM, Carey IM, Harris T, DeWilde S, Cook DG.  Antipsychotic prescribing to older people living in care homes and the community in England and Wales. Int J Geriatric Psych 2011;26:423-34 (doi: 10.1002/gps.2557)

191 Rodriguez S, Cook DG, Gaunt TR, Nightingale C, Whincup PH, Day INM.  Combined analysis of CHRNA5, CHRNA3 and CYP2A6 in relation to adolescent smoking behaviour. J Psychopharmacol 2011;25:915-23 (DOI:10.1177/0269881111405352)

192 Harris T, Shah SM, Carey IM, DeWilde S, Cook DG.  Depression indicators in a national sample of older community and care home patients: applying the Quality and Outcomes Framework. BJGP 2011;61:135-138 (doi:10.3399/bjgp11X556281)

193 Nightingale CM, Rudnicka AR, Owen CG, Cook DG, Whincup PH. Patterns of body size and adiposity among UK children of South Asian, black African-Caribbean and white European origin: Child Heart and Health Study in England (CHASE).  IJE 2011;40:33-44  (doi:10.1093/ije/dyq180)

194 Shah SM, Carey IM, Harris T, DeWilde S, Cook DG.  Quality of chronic disease care of older people in care homes and the community in a primary care pay for performance system. BMJ 2011;342:d912 (doi:10.1136/bmj.d912)

*195 Jones LL, Hashim A, McKeever T, Cook DG, Britton J, Leonardi-Bee J. Parental and Household Smoking and the Increased Risk of Bronchitis, Bronchiolitis and other Lower Respiratory Infection in Infancy and Childhood: Systematic Review and Meta-Analysis. Respiratory Research 2011;12:5 (doi:10.1186/1465-9921-12-5)

196 McMinn AM, van Sluijs EMF, Nightingale CM, Griffin SJ, Cook DG, Owen CG, Rudnicka AR, Whincup PH. Family and home correlates of children’s physical activity in a multi-ethnic population: Child Heart and Health Study in England (CHASE) Int J Behav Nutrition & Physical Activity 2011; 8:11 (doi:10.1186/1479-5868-8-11)

197 Owen CG, Rudnicka AR, Nightingale C|M, Mullen R, Barman SA, Sattar N, Cook DG, Whincup PH. Retinal arteriolar tortuosity and cardiovascular risk factors in a multiethnic population study of 10 year old children: the Child Heart And health Study in England (CHASE). Arterioscler Thromb Vasc Biol  2011:31:1933-8 (DOI: 10.1161/ATVBAHA.111.225219)

198 Shah SM, Carey IM, Owen CG, Harris T, DeWilde S, Cook DG.  Does beta-adrenoceptor blocker therapy improve cancer survival?  Findings from a population based retrospective cohort study. Brit J Clin Pharmacol 2011;72:157-61 (DOI:10.111/j.1365-2125.03980.x)

199 Owen CG, Whincup PH, Cook DG. Breast-feeding and cardiovascular risk factors and outcomes in later life: evidence from epidemiological studies. Proc Nutr Soc 2011;70:478-84 (doi:10.1017/S0029665111000590)

200 Shah SM, Carey IM, Harris T, DeWilde S, Cook DG.  The impact of dementia on influenza vaccination uptake in community and care home residents.  Age & Ageing 2012;41:64-9 (doi: 10.1093/ageing/afr135)

201 Jones LL, Hassanien A, Cook DG, Britton JR, Leonardi-Bee J.  Parental smoking and the risk of middle ear disease in children: a systematic review and meta-analysis. Arch Pediatr Adolesc Med 2012;166:18-27 (doi:10.1001/archpediatrics.2011.158)

202 Harris T, Carey IM, Shah SM, DeWilde S, Cook DG.  Antidepressant prescribing in older primary care patients in community and care home settings in England and Wales. J Am Med Dir Assoc 2012; 13:41-7  (DOI: 10.1016/j.jamda.2010.09.005)

203 Owen CG, Nightingale CM, Rudnicka AR, van Sluijs EMF, Griffin SJ, Ekelund U, Cook DG, Whincup PH.  Travel to school and physical activity levels in 9-10 year-old UK children of different ethnic origin: Child Heart and health Study in England (CHASE) PloS ONE 2012; 7(2):e30932 (doi:10.1371/journal.pone.0030932)

**204 Burke H, Leonardi-Bee J, Hashim A, Pine-Abata H, Chen Y, Cook DG, Britton JR, McKeever TM. Prenatal and passive smoke exposure and incidence of asthma and wheeze: systematic review and meta-analysis. Pediatrics 2012;129:735-44 (doi: 10.1542/peds.2011-2196)

205 Carey IM, DeWilde S, Shah SM, Harris T, Whincup PH, Cook DG.  Statin use after first myocardial infarction in UK men and women from 1997-2006: who started and who continued treatment?  NMCD 2012;22:400-8 (doi:10.1016/j.numecd.2010.09.010)

206 Shah SM, Carey IM, Harris T, DeWilde S, Cook DG.  Quality of prescribing in care homes and the community in England and Wales. Br J Gen Pract 2012;62:e329-36 (doi:10.3399/bjgp12X641447)

*207 Rudnicka A, Jarrar Z, Wormald R, Cook DG, Fletcher A, Owen CG. Age and gender variations in age related macular degeneration prevalence in populations of European ancestry: systematic review. Ophthalmology 2012;119:571-80 (doi:10.1016/j.ophtha.2011.09.027)

*208 Owen CG, Jarrar Z, Wormald R, Cook DG, Fletcher AE, Rudnicka AR. The estimated prevalence and incidence of late stage age related macular degeneration in the UK. Brit J Ophthalmology 2012;96:752-6 (doi:10.1136/bjophthalmol-2011-301109)

209 Shah SM, Carey IM, Harris T, DeWilde S, Victor CR, Cook DG. Do good health and material circumstances protect older people from the increase in mortality after bereavement? Am J Epidemiol 2012;176:689-98 (doi: 10.1093/aqje/kws 162)

210 Thomas C, Nightingale CM, Donin AS, Rudnicka AR, Owen CG, Sattar N, Cook DG, Whincup PH. Socio-economic position and Type 2 Diabetes Risk Factor Patterns in UK Children of South Asian, Black African-Caribbean and White European Origin. PLoS one 2012; 7(3):e32619 (doi:10.1371/journal.pone.0032619)

211 Whincup PH, Nightingale CM, Owen CJ, Rapala A, Bhowruth DJ, Prescott MH, Ellins EA, Donin AS, Massi S, Rudnicka AR, Sattar N, Cook DG, Deanfield JE.  Early emergence of ethnic differences in carotid intimal-medial thickness between black African Caribbeans and white Europeans: evidence from the Child Heart And health Study in England (CHASE). Stroke 2012;43:1747-54 (DOI: 10.1161/STROKEAHA.111.644955)

212 Nightingale CM, Krishnaveni GV, Rudnicka AR, Owen CG, Veena SR, Hill JC, Cook DG, Fall CHD, Whincup PH.  Cardiometabolic risk markers in Indian children: comparison with UK Indian and white European children. PLoS one 2012;7(4):e36236 (doi:10.1371/journal.pone.0036236)

213 Massi S, Nightingale CM, Day INM, Guthrie P, Rumley A, Lowe GDO, von Zglinicki T, D’Aiuto F, Taddei S, Klein N, Salpea K, Cook DG, Humphries SE, Whincup PH, Deanfield J.  Inflammation and Not Cardiovascular Risk Factors Is Associated With Short Leukocyte Telomere Length in 13-to 16-Year-Old Adolescents. Arterioscler Thromb Vasc Biol 2012;32:2029-U655 (DOI: 10.1161/ATVBAHA.112.250589)

214 Peters H, Whincup PH, Cook DG, Law C, Li L. Trends in blood pressure in 9-11 year old children in the UK 1980-2008: the impact of obesity.  J Hypertension 2012;30:1708-17 (DOI:10.1097/HJH.0b013e3283562a6b)

215 217 Thomas C, Nightingale CM, Donin AS, Rudnicka AR, Owen CG, Cook DG, Whincup PH. Ethnic and socio-economic influences on childhood blood pressure: the Child Heart and  Health Study in England (CHASE). J Hypertension 2012; 30:2090-7 (doi: 10.1097/HJH.0b013e32835837c9)

216 Shah SM, Carey IM, Harris T, DeWilde S, Cook DG.  Mortality in older care home residents in England and Wales.  Age & Ageing 2013;42:209-15 (doi: 10.1093/ageing/afs174)

217 Harris T, Kerry S, Victor C, Ekelund U, Woodcock A, Illiffe S, Whincup P, Beighton C, Ussher M, David L, Brewin D, Adams F, Rogers A, Cook D. Randomised controlled trial of a complex intervention by primary care nurses to increase walking in patients aged 60-74 years: protocol of the PACE-Lift (Pedometer Accelerometer Consultation Evaluation – Lift) trial. BMC Public Health 2013;13:5 (DOI: 10.1186/1471-2458-13-5)

218 Atkinson RW, Carey IM, Kent AJ, van Staa TP, Anderson HR, Cook DG.  Long term exposure to outdoor air pollution and incidence of cardiovascular diseases. Epidemiology 2013;24:44-53 (doi:10.1097/EDE.0b013e318276ccb8)

219 Carey IM, Shah SM, Harris T, DeWilde S, Cook DG. A new simple comorbidity score predicts mortality and better explains between practice variations than the Charlson Index. J Clin Epidemiol 2013;66:436-44. (doi:10.1016/j.jclinepi.2012.10.012)

220 Shah SM, Carey IM, Harris T, DeWilde S, Victor CR, Cook DG. The effect of unexpected bereavement on mortality in older couples.  Am J Public Health 2013;103:1140-5 (doi:10.2105/AJPH.2012.301050)

221 Nightingale CM, Rudnicka AR, Owen CG, Wells JCK, Sattar N, Cook DG, Whincup PH. Influence of adiposity on insulin resistance glycaemia markers among UK children of South Asian, black African-Caribbean and white European origin: Child Heart and health Study in England (CHASE). Diabetes Care 2013;36:1712-9 (doi:10.2337/dc12-1726)

222 Carey IM, Atkinson R, Kent A, van Staa TP, Cook DG, Anderson HR. Mortality associations with long-term exposure to outdoor air pollution in a national English cohort. AJRCCM  2013;187:1226-33 (doi:10.1164/rccm.201210-1758OC)

223 Nightingale CM, Rudnicka AR, Owen CG, Donnin AS, Newton SL, Furness CA, Howard EL, Gillings R, Wells JCK, Cook DG, Whincup PH.  Are ethnic and gender specific equations needed to derive fat free mass from biolelectrical impedence in children of South Asian, black African-Caribbean and white European origin? Results of the Assessment of Body Composition in Children Study.  PLoS ONE  2013 8(10) e76426 (doi:10.1371/journal.pone.0076426)

224 Shah SM, Carey IM, Harris T, DeWilde S, Victor CR, Cook DG. Initiation of  psychotropic medication after partner bereavement: a matched cohort study.  PLoS ONE 2013 8(11):e77734 (doi:10.1371/journal.pone.0077734)

225 Harris T, Kerry SM, Victor CR, Shah SM, Illiffe S, Ussher M, Ekelund U, Fox-Rushby J, Whincup P, David L, Brewin D, Ibison J, DeWilde S, Limb E, Anokye N, Furness C, Howard E, Dale R, Cook DG.  PACE UP (Pedometer And Consultation Evaluation – UP) - a pedometer-based walking intervention with and without practice nurse support in primary care patients aged 45-75 years: study protocol for a randomised controlled trial. Trials 2013;14:418 (doi:10.1186/1745-6215-14-418)

226 Shah SM, Carey IM, Harris T, DeWilde S, Victor CR, Cook DG. Impact of partner bereavement on quality of cardiovascular disease management. Circulation 2013;128:2745-2753 (DOI: 10.1161/CIRCULATIONAHA.113.004122)

227 Peters H, Whincup PH, Cook DG, Law C, Li L. Trends resting pulse rate in 9-11 year old children in the UK 1980-2008. Archives Disease Childhood 2014;99:10-14 (doi:10.1136/archdischild-2013-304699)

228 Donin AS, Nightingale CM, Owen CG, Rudnicka AR, Jebb SA, Ambrosini GL, Stephen AM, Cook DG, Whincup PH.  Dietary energy intake is associated with type 2 diabetes risk markers in children.  Diabetes Care 2014;37:116-123 (doi: 10.2337/dc13-1263)

229 Carey IM, Shah SM, Harris T, DeWilde S, Victor CR, Cook DG. Increased risk of acute cardiovascular events after partner bereavement? JAMA Intern Med 2014;174:598-605 (doi:10.1001/jamainternmed.2013.14558)

230 Rodgers A, Harris T, Victor C, Woodcock A, Limb E, Kerry S, Iliffe S, Whincup P, Ekeland U, Beighton C, Ussher M, Cook DG. Which Older People Decline Participation in a Primary Care Trial of Physical Activity and Why? Insights from a Mixed Methods Approach. BMC Geriatrics 2014 14:46 (doi:10.1186/1471-2318-14-46)

231 Donin AS, Nightingale CM, Owen CG, Rudnicka AR, Perkin MR, Jebb SA, Stephen AM, Sattar N, Cook DG, Whincup PH.  Regular breakfast consumption and Type 2 Diabetes Risk Markers in 9-10 year old children in the Child Heart and Health Study in England (CHASE): A Cross-Sectional Analysis. PLoS Med 2014;11 (9): e1001703 (doi:10.1371/journal.pmed.1001703)

232 Kapetanakis VV, Rudnicka AR, Wathern AK, Lennon L, Papacosta O, Cook DG, Wannamethee SG, Whincup PH, Owen CG.  Adiposity in early, middle and later adult life and cardiometabolic risk markers in later life; findings from the British Regional Heart Study. PloS ONE 2014 9(12): e114289 (doi:10.1371/journal.pone.0114289)

233 Wade KH, Forouhi NG, Cook DG, Johnson P, MacConnachie A, Morris RW, Rodriguez R, Ye Z, Ebrahim S, Padmanabhan S, Watt G, Bruckdorfer KR, Wareham NJ, Whincup PH, Chanock S, Sattar N, Lawlor DA, Davey-Smith G, Timpson NJ. Variation in the SLC23A1 gene does not influence cardio-metabolic outcomes to the extent expected given its association with L-ascorbic acid.  AJCN 2014 101:202-9 (doi:10.3945/ajcn.114.092981)

234 Normansell R, Holmes R, Victor C, Cook DG, Kerry S, Shah S, Illiffe S, Ussher M, Ekelund U, Fox-Rushby J, Whincup P, Harris T. Numbers are not the whole story: a qualitative exploration of barriers and facilitators to increased physical activity in a primary care based walking intervention BMC Public Health 2014;14:1272 (doi:10.1186/1471-2458-14-1272)

235 Atkinson RW, Carey IM, Kent A, van Staa TP, Anderson HR, Cook DG.  Long-term exposure to outdoor air pollution and the incidence of chronic lung disease in a national English cohort. Occup Environ Med 2015;72:42-8  (doi:10.1136/oemed-2014-102266)

236 Nightingale CM, Rudnicka AR, Owen CG, Newton SL, Bales JL, McKay CM, Steer PJ, Lawlor DA, Satar N, Cook DG, Whincup PH. Birthweight and risk markers for type 2 diabetes and cardiovascular disease in childhood: the Child Heart and Health Study in England (CHASE).  Diabetalogia 2015;58(3):474-484 (doi:10.1007/s00125-014-3474-7)

237 Harris T, Kerry SM, Victor CR, Ekelund U, Woodcock A, Iliffe S, Whincup PH, Beighton C, Ussher M, Limb ES, David L, Brewin D, Adams F, Rogers A, Cook DG.  A primary care nurse-delivered intervention in older adults: PACE(Pedometer Accelerometer Consultation Evaluation)-Lift cluster randomised controlled trial.  PLOS MED 2015;12(2):e1001783 (DOI:10.1371/journal.pmed.1001783)

238 Bayley A, de Zoysa N, Cook DG, Whincup PH, Stahl D, Twist K, Ridge K, McCrone P, Treasure J, Ashworth M, Greenough A, Blythe C, Winkley K, Ismail K.  Comparing the effectiveness of enhanced MOtiVational intErviewing InTervention (MOVE-IT) with usual care for reducing cardiovascular risk in high risk subjects: study protocol for a randomised controlled trial.  Trials 2015;16:112 (DOI:10.1186/s13063-015-0593-5)

239 Rudnicka AR, Kapetanakis VV, Jarrar Z, Wathern AK, Wormald R, Fletcher AE, Cook DG, Owen CG. Incidence of late stage age related macular degeneration in American Whites: systematic review and meta-analysis. Am J Ophthalmol 2015;160: 85-93 (DOI:10.1016/j.ajo.2015.04.003)

241 Ahmad S, Harris T, Limb E, Kerry S, Victor C, Ekelund U, Illiffe S, Whincup P, Beighton C, Ussher M, Cook DG. Evaluation of reliability and validity of the General Practice Physical Activity Questionnaire (GPPAQ) in 60-74 year old primary care patients. BMC Fam Pract 2015;16:113 (DOI:10.1186/s12875-015-0324-8)

241 Barone-Adesi F, Dent JE, Dajnac D, Beavers S, Anderson HR, Kelly FJ, Cook DG, Whincup PH. Long-term exposure to traffic pollutants and lung function in children: cross sectional study and meta-analysis. PLoS ONE 2015;10(11): e0142565 (DOI:10.1371/journal.pone.0142565)

242 Owen CG, Kapetanakis VV, Rudnicka AR, Wathern AK, Lennon L, Papacosta O, Cook DG, Wannamethee SG, Whincup PH.  Body Mass Index in early and middle adult life: prospective associations with myocardial infarction, stroke and diabetes over a 30 year period; the British Regional Heart Study. BMJ Open 2015;5:e008105 (doi:10.1136/bmjopen-2015-008105)

243 Beighton C, Victor C, Normansell R, Cook D, Kerry S, Illiffe S, Ussher M, Whincup P, Fox-Rushby J, Woodcock A, Harris T. “It’s not just about walking….it’s the practice nurse that makes it work”: a qualitative exploration of the views of practice nurses delivering complex physical activity interventions in primary care. BMC Public Health 2015;15:1236 (DOI: 10.1186/s12889-015-2568-6)

244 Donin AS, Dent JE, Nightingale CM, Sattar N, Owen CG, Rudnicka AR, Perkin MR, Stephen AM, Jebb SA, Cook DG, Whincup PH.  Fruit, vegetable, vitamin C intakes and plasma vitamin C: cross-sectional associations with insulin resistance and glycaemia in 9-10 year-old children. Diabetic Medicine 2016;33:307-315 (DOI: 10.1111/dme.13006)

245 Pearson-Stuttard J, Blundell S, Harris T, Cook DG, Critchley J. Diabetes and infection: assessing the association with glycaemic control in population-based studies. Lancet Diabetes & Endocrinology 2016;4:148-58 (DOI: 10.1016/S2213-8587(15)00379-4)

246 Carey IM, Shah SM, Hosking F, DeWilde S, Harris T, Cook DG. Health characteristics and consultation patterns of people with intellectual disability: a cross-sectional database study in English general practice. BJGP 2016;66:190-191 (full version DOI:10.3399/bjgp16X684301)

247 Shah SM, Carey IM, DeWilde S, Harris T, Victor CR, Cook DG. The mental health and mortality impact of death of a partner with dementia.  Int J Geriatr Psychiatry 2016;31:929-37 (DOI:10.1002/gps.4411)

248 Kapetanakis VV, Chan MPY, Foster PJ, Cook DG, Owen CG, Rudnicka AR. Global variations and time trends in the prevalence of Primary Open Angle Glaucoma (POAG); a systematic review and meta-analysis. Br J Ophthalmol 2016;100:86–93  (doi:10.1136/bjophthmol-2015-307223)

249 Rudnicka AR, Kapetanakis V, Wathern A, Logan NS, Gilmartin B, Whincup PH, Cook DG, Owen CG. Global variations and time trends in the prevalence of childhood myopia, a systematic review: implications for aetiology and prevention. Br J Ophthalmol 2016;100:882-90 (DOI:10.1136/bjophthalmol-2015-307724)

250 Hosking FJ, Carey IM, Shah SM, DeWilde S, Harris T, Beighton CA, Cook DG. Mortality disparities and potentially avoidable mortality in adults with intellectual disability. AJPH 2016;106:1483-90 (DOI:10.2105/AJPH.2016.303240)

251 Nightingale CM, Donin AS, Kerry SR, Owen CG, Rudnicka AR, Brage S, Westgate KL, Ekelund U, Cook DG, Whincup PH. Cross-sectional study of ethnic differences in physical fitness among children of South Asian, black African-Caribbean and white European origin: the Child Heart And health Study in England (CHASE). BMJ Open 2016;6:e011131 (DOI:10.1136/bmjopen-2016-011131)

252 Lum S, Bountziouka V, Quanjer P, Sonnappa S, Wade A, Beardsmore C, Chhabra SK, Chudasama RK, Cook DG, Harding S, Kuehni CE, Prasad KVV, Whincup PH, Lee S, Stocks J. Challenges in collating spirometry reference data for South-Asian children: an observational study. PLoS ONE 2016;11(4):e0154336 (DOI:10.1371/journal.pone.0154336)

 

253 Normansell R, Holmes R, Victor C, Cook DG, Kerry S, Iliffe S, Ussher M, Fox-Rushby J, Whincup P, Harris T. Exploring non-participation in primary care physical activity interventions: PACE-UP trial interview findings. Trials 2016;17:178 (DOI:10.1186/s13063-016-1299-z)

254 Carey IM, Anderson HR, Atkinson RA, Beevers S, Cook DG, Dajnak D, Gulliver J, Kelly F. Traffic pollution and the incidence of cardio-respiratory outcomes in an adult cohort in London. Occup Environ Med 2016;73:849-56  (DOI:10.1136/oemed-2015-103531)

255 Victor CR, Rogers A, Woodcock A, Beighton C, Cook DG,  Kerry SM, Iliffe S, Whincup P, Ussher M, Harris T. What factors support older people to increase their physical activity levels? An exploratory analysis of the experiences of PACE-Lift trial participants. Archiv Gerontol Geriatr 2016;67:1-6

256 Ram B, Nightingale CM, Hudda MT, Kapetanakis VV, Ellaway A, Cooper AR, Page A, Lewis D, Cummins S, Giles-Corti B, Whincup PH, Cook DG, Rudnicka AR, Owen CG. Cohort Profile: Examining Neighbourhood Activities in Built Living Environments in London: the ENABLE London - Olympic Park cohort. BMJ Open 2016;6:e012643 (DOI:10.1136/bmjopen-2016-012643)

257 Carey IM, Hosking FJ, Harris T, DeWilde S, Beighton C, Shah S, Cook DG. Do health checks for adults with intellectual disability reduce emergency hospital admissions? Evaluation of a natural experiment. J Epidemiol Community Health 2017;71:52–58 (DOI:10.1136/jech-2016-207557)

258 Harris T, Kerry SM, Limb E, Victor CR, Iliffe S, Shah SM, Ussher M, Whincup PH, Ekelund U ,Fox-Rushby J, Furness C, Anokye N, Ibison J, DeWilde S, David L, Howard E, Dale R, Smith J, Cook DG. Effect of a primary care walking intervention with and without nurse support on physical activity levels in 45-75 year olds: The Pedometer And Consultation Evaluation (PACE-UP) cluster randomised controlled trial. PLOS Med 2017;14:e1002210 (DOI:10.1371/journal.pmed.1002210)

259 Nightingale CM, Rudnicka AR, Donin AS, Sattar N, Cook DG, Whincup PH, Owen CG. Screen time is associated with adiposity and insulin resistance in children. Arch Dis Child 2017;102:612-6 (DOI:10.1136/archdischild-2016-312016)

260 Hosking FJ, Carey IM, Harris T, DeWilde S, Beighton C, Cook DG. Preventable Emergency Hospital Admissions among Adults with Intellectual Disability Ann Fam Med 2017;15:462-70 (DOI: 10.1370/afm.2104)

261 Hudda M, Nightingale C, Donin A, Fewtrell M, Haroun D, Lum S, Williams J,  Owen C, Rudnicka A, Wells J, Cook DG, Whincup PH. Body mass index adjustments to increase the validity of body fatness assessment in UK black African and South Asian children. IJO 2017;41:1048–55 (DOI:10.1038/ijo.2017.75)

262 Carey IM, Hosking FJ, Harris T, DeWilde S, Beighton C, Cook DG. An evaluation of the effectiveness of annual health checks and quality of health care for adults with intellectual disability: an observational study using a primary care database. Health Serv Deliv Res 2017;5 (25) (DOI:10.3310/hsdr05250).

263 Rudnicka AR, Nightingale CM, Donin AS, Sattar N, Cook DG, Whincup PH, Owen CG. Sleep duration and risk of type 2 diabetes. Pediatrics 2017;140(3):e20170338 (DOI: 10.1542/ peds. 2017- 0338)

264 Ram B , Shankar A, Nightingale CM, Giles-Corti B, Ellaway A, Cooper AR, Page A, Cummins S, Lewis D, Whincup PH, Cook DG, Alicja Rudnicka, Owen CG. Comparisons of depression, anxiety, well-being, and perceptions of the built environment amongst adults seeking social, intermediate and market-rent accommodation in the former London Olympic Athletes’ Village. Health & Place 2017;48:31-9 (DOI:10.1016/j.healthplace.2017.09.001)

265 Beighton C, Victor C, Carey IM, Hosking FJ, DeWilde S, Cook DG, Manners P, Harris T. “I’m sure we made it a better study …” Parent carers’ and adults with intellectual disabilities’ experience of involvement in a research study. J Intellectual Disabilities 2017 (DOI:10.1177/1744629517723485)

266 Carey IM, Hosking FJ, Harris T, DeWilde S, Beighton C, Cook DG. An evaluation of the effectiveness of annual health checks and quality of health care for adults with intellectual disability: an observational study using a primary care database. Health Serv Deliv Res 2017;5(25) (DOI:10.3310/hsdr05250)

267 Hudda MT, Nightingale CM, Donin AS, Owen CG, Rudnicka AR, Wells JCK, Rutter H, Cook DG, Whincup PH. Patterns of childhood body mass index, overweight and obesity in South Asian and Black participants in the English National Child Measurement Programme: effect of applying BMI adjustments standardizing for ethnic differences in BMI-body fatness associations. IJO 2018;42:662-70 (DOI:10.1038/ijo.2017.272)

268 Donin A, Nightingale C, Owen CG, Rudnicka AR, Cook DG, Whincup PH. Takeaway meal consumption and risk markers for coronary heart disease, type 2 diabetes and obesity in children aged 9-10 years: a cross-sectional study. Arch Dis Child 2018;103:431–436. (DOI:10.1136/archdischild-2017-312981)

269 Hudda MT, Nightingale CM, Donin AS, Owen CG, Rudnicka AR, Wells JCK, Rutter H, Cook DG, Whincup PH.  Reassessing ethnic differences in mean body mass index and their changes between 2007 and 2013 in English children. Obesity 2018;26:412-419 (DOI:10.1002/oby.22091)

270 Carey IM, Critchley JA, DeWilde S, Harris T, Hosking FJ, Cook DG. Risk of infection in type 1 and type 2 diabetes compared to the general population: a matched cohort study. Diabetes Care 2018;41:513-21 (DOI:10.2337/dc17-2131)  

271 Nightingale CM, Rudnicka AR,  Kerry-Barnard SR, Donin AS, Brage S, Westgate KL, Ekelund U, Cook DG, Owen CG, Whincup PH.  The contribution of physical fitness to individual and ethnic differences in risk markers for type 2 diabetes in children: the Child Heart and health Study in England (CHASE). Pediatric Diabetes 2018:1-8 (DOI:10.1111/pedi.12637)

272 Furness C, Howard E; Limb L, Cook DG, Kerry S, Wahlich C, Victor C, Ekelund U, Iliffe S, Ussher M, Whincup P, Fox-Rushby J, DeWilde S, Harris T.  Relating process evaluation measures to complex intervention outcomes: findings from the PACE-UP primary care pedometer-based walking trial. BMC Trials 2018;19:58 (DOI: DOI 10.1186/s13063-017-2428-z)

273 Harris T, Kerry SM, Limb ES, Furness C, Wahlich C, Victor CR, Iliffe S, Whincup PH, Ussher M, Ekelund U, Fox-Rushby J, Ibison J, DeWilde S, McKay C, Cook DG. Physical activity levels in adults and older adults 3-4 years after pedometer-based walking intervention: Long-term follow-up of participants from two randomised controlled trials in UK primary care. PLOS MED 2018;15(3):e1002526 (DOI:10.1371/journal.pmed.1002526)

274 Kerry S, Morgan K, Limb E, Cook DG, Watson C, Carey I, DeWilde S, Victor C, Iliffe S, Whincup P, Ussher M, Ekelund U, Fox-Rushby J, Ibison J, Harris T. Interpreting population reach of a large, successful physical activity trial delivered through primary care. BMC Public Health 2018;18:170 (DOI 10.1186/s12889-018-5034-4)

275 Ludwig VM, Bayley A, Cook DG, Stahl D, Treasure JL, Ashworth M, Greenough A, Winkley K, Bornstein SR, Ismail K. Association between depressive syptoms and objectively measured daily step count in individuals at high risk of cardiovascular disease in South London: a cross-sectional study. BMJ Open 2018;8:e020942 (DOI:10.1136/bmjopen-2017-020942)

276 Critchley J, Carey IM, Harris T, DeWilde S, Hosking FJ, Cook DG. Poor glycaemic control is associated with increased infection risk and risk of serious infections among DM patients with both type 1 and type 2 DM in a large primary care dataset. Diabetes Care 2018;41:2127-2135 (DOI:10.2337/dc18-0287)

277 Carey IM, Cook DG, Anderson HR, Strachan DP, Atkinson RA, Gulliver, Beevers, Kelly F. Are noise and air pollution related to the incidence of dementia?  A cohort study in London, England.  BMJ Open 2018;8:e022404 (DOI:10.1136/bmjopen-2018-022404)

278 Proctor DS, Page AS, Cooper AR, Nightingale CM, Ram B, Rudnicka AR, Whincup PH, Clary C, Lewis D, Cummins S, Ellaway A, Giles-Corti B, Cook DG, Owen CG. An open-source method to identify active travel from hip-worn accelerometer, GPS and GIS data. IJBNPA 2018;15:91 (DOI:10.1186/s12966-018-0724-y)

279 Nightingale CM, Rudnicka AR, Ram B, Shankar A, Proctor D, Page AS, Ellaway a, Giles-Corti B, Clary C, Lewis D, Cummins S, Whincup PH, Cook DG, Owen CG.  Housing, neighbourhood and sociodemographic associations with adult levels of physical activity and adiposity: baseline findings for the ENABLE London Study. BMJ Open 2018;8:e021257 (DOI:10.1136/bmjopen-2017-021257)

280 Anokye N, Fox-Rushby J, Sanghera S, Cook DG, Elizabeth L, Furness C, Kerry S, Victor C, Iliffe S, Ussher M, Whincup PH, Ekelund U, DeWilde S, Harris T. The short-term and long-term cost-effectiveness of a pedometer-based exercise intervention in primary care: A within-trial analysis and beyond-trial modelling. BMJ Open 2018;8:e021978. (DOI:10.1136/ bmjopen-2018-021978)

281 Bayley A, Stahl D, Ashworth M, Cook DG, Whincup PH, Treasure J, Greenough A, Ridge K, Winkley K, Ismail K. Response bias to a randomised controlled trial of a lifestyle intervention in people at high risk of cardiovascular disease: a cross-sectional analysis. BMC Public Health 2018 18:1092 (DOI: 10.1186/s12889-018-5939-y)

282 Hudda MT, Donin AS, Owen CG, Rudnicka AR, Sattar N, Cook DG, Whincup PH, Nightingale CM. Exploring the use of adjusted body mass index thresholds based on equivalent insulin resistance for defining overweight and obesity in UK South Asian children.  IJO 2019 43:1440-3 (DOI:10.1038/s41366-018-0279-7)

283 Limb E, Ahmad S, Cook DG, Kerry S, Ekelund U, Whincup PH, Victor C, Illife S, Ussher M, Fox-Rushby J, Watson C, Ibison J, De Wilde S, Harris T. Measuring change in trials of physical activity interventions: a comparison of self-report questionnaire and accelerometry within the PACE-UP trial. Int J Behaviour Nutrit & Physical Activity 2019;16:10 (DOI:10.1186/s12966-018-0762-5)

284 Harris T, Limb ES, Hosking F, Carey I,  DeWilde S, Furness C, Wahlich C, Ahmad S, Kerry SM, Whincup PH, Victor CR, Ussher M, Iliffe S, Ekelund U, Fox-Rushby J, Ibison J, Cook DG. Effect of pedometer-based walking interventions on long-term health outcomes: prospective 4-year follow-up of two randomised controlled trials using routine primary care data. PLOS Med 2019 16(6):e1002836 (DOI: 10.1371/journal.pmed.1002836)

285 Nightingale CM, Limb ES, Ram B, Shankar A, Clary C, Lewis D, Cummins S, Proctor D, Cooper AR, Page AS, Ellaway A, Giles-Corti B, Whincup PH, Rudnicka AR, Cook DG, Owen CO. The effect of moving to East Village, the former London 2012 Olympic and Paralympic Games Athlete’s Village, on Physical Activity and adiposity ( ENABLE London): a cohort study.  Lancet Public Health 2019 4(8):e421 (DOI:10.1016/S2468-2667(19)30133-1)

286 Hudda M, Fewtrell MS, Haroun D, Lum S, Williams JE, Wells JC, Riley RD, Owen CG, Cook DG, Rudnicka A, Whincup PH, Nightingale C,. Development and validation of a prediction model for fat mass in children and adolescents: meta-analysis using individual Participant data. BMJ 2019: 2019;366:l4293 (DOI: 10.1136/bmj.l4293)

287 Kimpton JE, Carey IM, Threapleton CJD, Robinson A, Harris T, Cook DG, DeWilde S, Baker EH.  Longitudinal exposure of English primary care patients to pharmacogenomic drugs: an analysis to inform design of pre-emptive pharmacogenomic testing. Br J Clin Pharmacol 2019;85:2734-46 (DOI: 10.1111/bcp.14100)

288 Czwikla G, Boen F, Cook DG, de Jong J, Harris T, Hilz LK, Iliffe S, Morris R, Muellmann S, Peels DA, Pischke CR, Schüz B, Stevens M, van Lenthe FJ, Vanderlinden J, Bolte G. Equity-specific effects of interventions to promote physical activity among middle-aged and older adults: Development of a collaborative equity-specific re-analysis strategy. Int. J. Environ. Res. Public Health 2019;16:3195 (DOI:10.3390/ ijerph16173195)

289 Critchley J, Carey IM, Harris T, DeWilde S, Hosking FJ, Cook DG.  Variability in glycaemic control and risk of poor outcomes among people with type 2 diabetes in a large primary care cohort study. Diabetes Care 2019; (DOI:10.2337/dc19-0848)

290 Ismail K, Bayley A, Twist K, Stewart K, Ridge K, Britneff E, Greenough A, Ashworth M, Rundle J, Cook D, Whincup P, Treasure J, Crone P, Winkley K, Stahl D. Reducing weight and increasing physical activity in people at high risk of cardiovascular disease: a randomised controlled trial comparing the effect of enhanced motivational interviewing intervention with usual care. Heart 2019 (DOI:10.1136/heartjnl-2019-315656)

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