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St George's Professor Richard Atkinson research has played an important role in influencing policy decisions around options for reducing nitrogen dioxide emissions.
Close integration with St George’s Hospital, clinicians and public health physicians ensures that the institute’s research addresses clinical priorities.
Sharing the same site in south west London, the Institute for Infection and Immunity and St George's Hospital work closely together to ensure new knowledge and technologies generated by research are quickly applied in a clinical setting.
As an indicator of this close integration, about a half of our principal investigators hold honorary clinical contracts at St George’s Hospital – one of the UK’s leading teaching hospitals, with more than 1000 beds. Many other hospital clinicians advise and contribute to our research.
Key clinical facilities include the specialist adult and paediatric infection units, which are run by clinical academics based in the institute. The paediatric unit is a paediatric infectious disease referral centre and a UK Centre of Excellence in the treatment of complex infections in children. Both units incorporate purpose-built specialist infectious disease wards, with negative-pressure rooms for containment isolation. We diagnose and treat a diverse range of infections from all over the world, reflecting the internationally diverse community we serve.
The institute belongs to the South London National Institute for Health Research (NIHR) Collaboration for Leadership in Applied Health Research and Care (CLAHRC) and leads its infection theme.
We also have well-established links to Public Health England. Furthermore, our scientists are engaged in national policy and government strategy for several areas of infection.
Our infrastructure facilitates a wide range of studies focused on clinical application in diagnostics, therapeutics and vaccinology. In the Centre for Diagnostics and Antimicrobial Resistance, multiple diagnostic approaches are being developed and evaluated for use in the UK and developing world. A number of potential new therapeutics have emerged from our research. We are leading and contributing to multiple national and international trials to improve use of anti-infective drugs. Our research also has impact on vaccine development, not only for infectious diseases but also as a route to innovative cancer treatments.
We focus on the epidemiology of vaccine-preventable diseases, human clinical trials of paediatric and adult vaccines and vaccines against infectious diseases plaguing the most underprivileged members of the world.
Using advanced sequencing technology and computational methods, we can unravel the secrets of the bacterial genome.
Professor Jodi Lindsay’s genomic studies are providing novel insights into DNA transfer in methicillin-resistant Staphylococcus aureus (MRSA), and how it adapts to hospital environments.
Professor Nidhi Sofat works on the causes of pain and inflammation in musculoskeletal diseases using a bench-to-bedside experimental approach.
Dr Wai Liu was the first to show that the order in which cannabinoids and chemotherapy are used is a key determinant in the overall effectiveness of the treatment.
Dr Sebastian Fuller, lead for the ADREU Social Science programme, is investigating facilitators and barriers to implementation of diagnostics in sexual health clinics across the UK.
Clinical microbiologist Dr Tim Planche sits at the interface between research and clinical practice.
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