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Dr Joe Westaby

Clinical Lecturer in Histopathology
NIHR Clinical Lecturer in Histopathology, Cardiovascular Histopathologist and Autopsy Pathologist

Joe is an NIHR Clinical Lecturer in Histopathology based at St George’s, University of London and in the South London Deanery. He studied Graduate Entry Medicine at The University of Nottingham and has trained in London since. He undertook an NIHR Academic Clinical Fellowship and PhD sponsored by Cardiac Risk in the Young in the Cardiac Risk in the Young Cardiovascular Pathology Laboratories. His primary research interest is Sudden Cardiac Death. He also undertakes coronial autopsies for the Inner West London Coroner.

Joe is specialising in both diagnostic and academic cardiovascular pathology, combining both diagnostic and autopsy material from our large referral database. He is now undertaking his own original research having completed a PhD at St George’s University. He is publishing peer reviewed articles and contributing to book chapters with Professor Sheppard. He is working closely with Professor Sheppard and developing expertise in all aspects of cardiovascular pathology. He has extensive teaching experience and has developed the cardiovascular course with both virtual and hybrid delivery. Together, he and Professor Sheppard are training other pathologists including general and forensic pathologists in this specialist field.

Joe started out doing a BSc in Biochemistry and Molecular Pathology at the University of Leeds. During this, he produced a clinical research thesis on hypertrophic cardiomyopathy. Wanting to specialise further, he chose to do an MSc in molecular biology and pathology of viruses at Imperial College, London. During this he produced a histopathological dissertation on the role of tissue factor in hepatocellular fibrosis caused by hepatitis c. Becoming captivated by pathology, Joe went on to do graduate entry medicine at the University of Nottingham. He undertook his special study module in forensic medicine and coronial medicine. During his foundation years in the South London Deanery he managed to maintain an interest in pathology by attending post mortems, reviewing bone marrow aspirates and trephines during a haematology placement and undertook a chemical pathology placement in which he spent a day a week in the histopathology department. He then obtained a position on the run through training programme of Histopathology. He was appointed as an Academic Clinical Fellow sponsored by the National Institute of Health Research at ST3 level. This fellowship enabled him to spend 9 months within the Cardiac Risk in the Young (CRY) laboratory where he gained experience in cardiac dissection and reporting whilst undertaking research into sudden cardiac death under the guidance of Professor Mary N Sheppard. He then progressed to undertake a PhD sponsored by Cardiac Risk in the Young in the CRY labs on the anatomical, histological and immunohistochemical findings in the normal heart and cardiomyopathies. He has now progressed to become an NIHR Clinical Lecturer in Histopathology.

Cardiac Risk in the Young Clinical Research Fellow and PhD student 2019-2022

NIHR Academic Clinical Fellow 2015-2019

Research Grant Pathological Society of Great Britain and Ireland, 2018

Glasgow 2020 Educational Fellowship BDIAP, 2019

Pathology representative for the Association for Inherited Cardiac Conditions council as pathology representative – 2022

Reader’s Choice 2021, Journal of Human Hypertension for paper “Characterisation of hypertensive heart disease: pathological insights from a sudden cardiac death cohort to inform clinical practice."

Young Investigator Award, The Society for Cardiovascular Pathology at the United States and Canadian Academy of Pathology, Los Angeles – 2020

Image of the Year 2022, St George’s University of London 

Best abstract for Obesity Cardiomyopathy: A distinct entity?, AICC annual conference, Glasgow, 2022

Runner Up Young Investigator Award for National Sudden Cardiac Death Autopsy Database, European Heart Rhythm Association, Barcelona, 2023

Joe's central research interest is sudden cardiac death but he has interests in inherited cardiac disease, autopsy, histology, pathology, cardiomyopathies, hypertensive heart disease and congenital heart disease. He works closely with cardiologists, pathologists (forensic, autopsy practitioners and hospital pathologists), basic scientists, statisticians and bioinformaticians. He has formed networks and collaborates within St George's, University of London, nationally and internationally.

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  • Westaby, Joseph, et al. "Obesity cardiomyopathy in sudden cardiac death: a distinct entity? a comparative study." JACC: Advances 2.5 (2023): 100414.
  • Sheppard, Mary N., et al. "Genetically determined cardiomyopathies at autopsy: the pivotal role of the pathologist in establishing the diagnosis and guiding family screening." Virchows Archiv (2023): 1-17.
  • Finocchiaro, Gherardo, et al. "Sudden cardiac death among adolescents in the United Kingdom." Journal of the American College of Cardiology 81.11 (2023): 1007-1017.
  • Sheppard, Mary N., et al. "Sudden arrhythmic death and cardiomyopathy are important causes of sudden cardiac death in the UK: results from a national coronial autopsy database." Histopathology (2023).
  • Ciliberti, Giuseppe, et al. "Coronary Artery Dissection and Myocardial Infarction With Nonobstructed Coronary Arteries: Insights From a UK Nationwide Autopsy-Based Registry." Arteriosclerosis, Thrombosis, and Vascular Biology (2023).
  • Chatrath, Nikhil, et al. "The Role of the Bicuspid Aortic Valve in Sudden Cardiac Death–Findings at Cardiac Autopsy." Cardiovascular Pathology (2023): 107527.
  • Finocchiaro, Gherardo, et al. "Sudden Cardiac Death During Exercise in Young Individuals With Hypertrophic Cardiomyopathy." Clinical Electrophysiology (2023).
  • Westaby, J. D., et al. "Effect of sex, age and body measurements on heart weight, atrial, ventricular, valvular and subepicardial fat measurements of the normal heart." Cardiovascular Pathology (2022): 107508.
  • Sexton, Mark, et al. "Fatal Case of Hypertrophic Cardiomyopathy in a Donor Heart: A Case Report." Transplantation Proceedings. Elsevier, 2022.
  • Cooper, S.T.E.; Westaby, J.D.; Haines, Z.H.R.; Malone, G.O.; Sheppard, M.N.; Meijles, D.N. Of Mouse and Man: Cross-Species Characterization of Hypertensive Cardiac Remodeling. Int. J. Mol. Sci. (2022)
  • Bhatia, Raghav T., et al. "Mitral valve abnormalities in decedents of sudden cardiac death due to hypertrophic cardiomyopathy and idiopathic left ventricular hypertrophy." Heart Rhythm (2022).
  • Coelho-Lima, Jose, Joseph Westaby, and Mary N. Sheppard. "Cardiac arrest with successful cardiopulmonary resuscitation and survival induce histologic changes that correlate with survival time and lead to misdiagnosis in sudden arrhythmic death syndrome." Resuscitation (2022).
  • Koushesh, S., et al. "The osteoarthritis bone score (OABS): a new histological scoring system for the characterisation of bone marrow lesions in osteoarthritis." Osteoarthritis and Cartilage (2022).
  • Finocchiaro, Gherardo, et al. "Association of Sexual Intercourse With Sudden Cardiac Death in Young Individuals in the United Kingdom." JAMA cardiology (2022).
  • Finocchiaro, Gherardo, et al. "Sudden Death in Female Athletes: Insights From a Large Regional Registry in the United Kingdom." Circulation 144.22 (2021): 1827-1829.
  • Miles, Chris, et al. "Biventricular myocardial fibrosis and sudden death in patients with Brugada syndrome." Journal of the American College of Cardiology 78.15 (2021): 1511-1521.
  • Ng, K. E., et al. "Early inflammation precedes cardiac fibrosis and heart failure in desmoglein 2 murine model of arrhythmogenic cardiomyopathy." Cell and Tissue Research (2021): 1-20.
  • Westaby, J. D., et al. "Characterisation of hypertensive heart disease: pathological insights from a sudden cardiac death cohort to inform clinical practice." Journal of Human Hypertension (2021): 1-8. (Reader’s Choice 2021)
  • Finocchiaro, Gherardo, et al. "Arrhythmogenic potential of myocardial disarray in hypertrophic cardiomyopathy: genetic basis, functional consequences and relation to sudden cardiac death." EP Europace (2021).
  • Cooper, Susanna TE, et al. "The role of endocarditis in sudden cardiac death: Highlighting the value of the autopsy, pathological features and cardiac complications." Cardiovascular Pathology 50 (2021): 107292.
  • Ciliberti, Giuseppe, et al. "Myocardial infarction with nonobstructed coronary arteries and sudden cardiac death: a clinical and pathological perspective." Circulation: Arrhythmia and Electrophysiology 13.7 (2020): e008302.
  • Miles, Chris, et al. "Morphometric characterization of collagen and fat in normal ventricular myocardium." Cardiovascular Pathology 48 (2020): 107224.
  • Westaby, Joseph D., et al. "Insights from examination of hearts from adults dying suddenly to the understanding of congenital cardiac malformations." Clinical Anatomy (2019).
  • Westaby, Joseph, and Mary N. Sheppard. "Letter by Westaby and Sheppard Regarding Article,“Sudden Cardiac Death in Hypertensive Patients”." Hypertension 74.2 (2019): e37-e37.
  • Mahmod, Masliza, et al. "Histological evidence for impaired myocardial perfusion reserve in severe aortic stenosis." JACC: Cardiovascular Imaging 12.11 (2019).
  • Miles, Chris, et al. "Sudden death and left ventricular involvement in arrhythmogenic cardiomyopathy." Circulation 139.15 (2019): 1786-1797.
  • Vazir, Ali, et al. "Can we remove scar and fibrosis from adult human myocardium?." European heart journal 40.12 (2019): 960-966.
  • Westaby, Joseph D., et al. "Primary ovarian malignant PEComa: a case report." International Journal of Gynecological Pathology 36.4 (2017): 400-404.
  • Rocha, Joana, et al. "IgG4-tubulointerstitial nephritis: a literature review following 5 cases in a single centre." Portuguese Journal of Nephrology & Hypertension 31.4 (2017): 254-261.
  • NIHR Clinical Lectureship in Histopathology, 2022-2026.
  • Cardiac Risk in the Young Clinical Fellowship and Clinical Lectureship, 2019-2024.
  • Glasgow 2020 Educational Fellowship of £2,500 from BDIAP, 2019.
  • Bursary from the Pathological Society to attend Leeds Pathology 2019.
  • Small grant of £10,000 from the Pathological Society, 2018.
  • Bursary from Pathological Society to attend the 10th Joint Meeting of the British Division of the International
  • Academy of Pathology and the Pathological Society of Great Britain & Ireland, Belfast Pathology 20-23rd June 2017.
  • Bursary from Pathological Society to attend the 6th National Academic Trainee Network Meeting, 18-19th June 2017, Belfast.
  • Bursary from BDIAP to attend the IAP/ESP meeting, Cologne, Germany, 25-29th September 2016.
  • NIHR Academic Clinical Fellow 2015-2019
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