Molecular and Clinical Sciences Section

Led by Head of Section Professor Katalin Torok, research in the Molecular and Cellular Sciences Section addresses molecular and cellular mechanisms of health and disease. Our research areas encompass:

• mechanisms of cell signalling in cell division
• neurotransmission
• endothelial and neuroendocrine function
• the physiology of aging and cancer.

We develop genetically encoded fluorescent sensors of cell signalling and neurotransmission and use state-of-the-art molecular biological, protein biophysical, fluorescence and imaging approaches to understand the molecular and cellular mechanisms of health and disease.

Researchers in molecular and cellular science

Learn more about some of our researchers and the work they do by clicking each of the sections below.

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Dr Anissa Chikh

Research aims to unravel novel pathways that regulate homeostasis and how dysregulation of these pathways leads to disease. 

Dr Bridget Bax

In vitro modelling of mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) using patient-derived induced pluripotent stem cells (iPSC).

Professor Dot Bennett

 Fluorescence image of senescent normal human melanocytes immunostained for proteins p16 (red) and 53BP1 (green) and with nuclei in blue (DAPI).  Maximal intensity Z projection, captured using a Nikon A1R confocal microscope.  From a study of upregulation of p16 in cell senescence.

Professor Tom Carter

Research works on the molecular regulation of von Willebrand factor (VWF) section by vascular endothelial cells. 

Dr Sue Cotterill

Assy for analysis of misincorporation by cancer related DNA polymerases. 

Dr Soo-Hyun Kim

Currently working on WDR11 to understand its function in ciliogenesis and how it contributes to neuroendocrine disorders such as Kallmann syndrome.

Dr Francisco Miralles

We use CRISPR/Cas9 to generate knockouts of both protein coding genes and non-protein coding genes to study how their loss-of-function affects cell proliferation and survival of various cancer cell lines.

Dr Suman Rice

Professor Katalin Torok

Optical probes for investigating cell signalling and neurotransmission