Tel: +44 (0) 208 725 3474
Email: daclark@sgul.ac.uk
Biography
After I completed my Biochemistry degree in Bristol, during which I did an intercalated year at GlaxoSmithKline, I went on to study for an MSc in the Molecular Biology and Pathology of Viruses at Imperial College London. As I was interested in immunology and virology I chose to do a PhD at the London School of Hygiene and Tropical Medicine where I worked on a viral protein (U83 chemokine) that modulates the human immune response to infections with HHV-6 which in infants causes Roseola; also known as exanthema subitum. The work involved studying cells whose migration and behaviour was effected by the viral chemokine. As a specific immune modulator, the viral chemokine had possible applications as a therapeutic for multiple sclerosis and/or HIV. After my PhD I spent one year in the University of California San Diego studying chemokines involved in autoimmune disorders. I returned to the UK and joined this group as a Postdoctoral Research Assistant where I am studying the immune response of vaccinees to a novel vaccine for combating the Ebola virus. The investigation is part of VEBCON (VSV‐EBola CONsortium) and is funded by the German Ministry for Education and Research (BMBF).
Key publications
Dodd J.S., Clark D., Muir R., Korpis C., Openshaw P.J., 2013
Endogenous IL-21 regulates pathogenic mucosal CD4 T-cell responses during enhanced RSV disease in mice.
Mucosal Immunol. 2013 Jul;6(4):704-17.
Clark D.J., Catusse J., Stacey A., Borrow P., Gompels U.A., 2013
Activation of CCR2+ human proinflammatory monocytes by human herpesvirus-6B chemokine N-terminal peptide. J Gen Virol. 2013 Jul;94(Pt 7):1624-35.