On this pathway you will be taught the essentials of conducting high-quality research through a range of core modules, and will gain a detailed knowledge of global health diseases before undertaking your research project. 

biomedical science

The MRes is made up of 180 credits. All modules are compulsory, and will equip you with the skills and knowledge to conduct high quality research. 

Core modules

Research methods15 credits
Statistics15 credits
Research project planning and management15 credits
Research project105 credits

Specialist module - Global Health Diseases

This 30 credit module deals with aetiology, pathology, clinical manifestations, prevention and treatment. Each disease is dealt with from a global perspective, including how the disease is dealt with in different contexts such as richer or poorer nations. You will be given overviews of epidemiology, surveillance, data gathering and organisation, global and national public health initiatives and the major organisations involved in disease control. The active research at St George’s into global disease will enable you to work on specific topics in this area. 

Past research projects

The substantive research project is worth 105 credits. Here are some examples of past student projects:

Mapping pain in people with OA using MRI scans and clinical scores

Aims: We want to establish how the structural changes in arthritis relate to pain.

Brief overview: We have been conducting the Pain Perception in Osteoarthritis study which has collected data from people with arthritis before they have surgery, and relates their pain to their level of damage in the tissue revealed by MRI scans.

Methods used for data collection: Data has already been collected from a large study dataset which will be analysed during the study.

Epidemiology of arbovirus infections in a tropical district in coastal Ecuador

Aims

  1. Measure age-dependent prevalence of IgG antibodies to dengue, chikungunya and Zika virus
  2. Estimate rates of infection with chikungunya and Zika virus during epidemics
  3. Describe epidemiology of dengue virus infections
  4. Identify risk factors for arbovirus infections, co-infections with individual viruses and household clustering of infections

Brief overview: There are very limited data on the epidemiology of arbovirus infections in Ecuador. A recent study from Esmeraldas Province, a poor coastal province in a tropical region of Ecuador where conditions are optimal for vector breeding and arbovirus transmission, suggested that dengue may have supplanted malaria as the primary cause of fever (Cifuentes et al, 2013). A recent epidemic of chikungunya virus is believed to have circulated through Esmeraldas Province in 2015 based on classic clinical presentation, and suspected cases of Zika virus infection have been reported from January 2016. Although all four serotypes of dengue virus are assumed to circulate within Esmeraldas Province, there are no published studies describing the epidemiology of infections with dengue, chikungunya and Zika virus infections. Given the asymptomatic nature of these infections, the burden of disease is likely to be substantially underestimated. We propose a serological assessment in the population using assays based on blood samples from evaluations of ongoing existing birth cohort at eight years of age and the children’s families.

Methods used for data collection: Arbovirus infections – specific IgG to dengue virus, chikungunya virus, and Zika virus infections by ELISA in already collected capillary blood samples. Socio-demographic risk factors.

Effects of parasite infections on childhood growth trajectories in an Ecuadorian birth cohort; analysis from birth to 5 years of age

Aims:

  1. To investigate growth trajectories of a birth cohort from birth to five years
  2. To investigate the odds of infections with enteric parasites during the first five years of life and how these may vary with age
  3. To explore the extent to which the presence of enteric parasites and subsequent resulting infections affect childhood growth trajectories
  4. To identify the extent to which other determinants contribute to childhood growth trajectories

Brief overview: There is anecdotal evidence that parasitic infections are associated with adverse effects in early childhood growth. However, there is little data which addresses this question, particularly in developing countries where the presence of parasites is endemic.

Methods used for data collection: This project used a birth cohort of 2,404 children that have been followed from birth to five years of age in rural Ecuador.


Last Updated: Tuesday, 21 March 2017 09:12