The PgCert ICAG consists of four modules to equip you with the neccessary skills and knowledge to advance your understanding in the interpretation and clinical application of genomic data.

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For a breakdown of the modules view the module overview

Core Modules

Understanding genetic technologies

  • Demonstrate knowledge and applicability of the principles behind commonly used molecular techniques
  • Evaluate which laboratory investigations are most suitable for a given clinical scenario
  • Critically review the processes used in issuing a laboratory report from sample checking to issuing of a diagnostic report
  • Demonstrate an in depth understanding of the methodology of at least four molecular genetic techniques
  • Design a panel of genes for analysis using next generation sequencing technologies applicable to a specific clinical phenotype

Clinical Interpretation of genomic data

  • Analyse the key features of a genetic variant which affect the prior likelihood of pathogenicity
  • Critically examine the clinical context within which a genetic variant will be interpreted
  • Apply in silico variant analysis tools to evaluate genetic variants
  • Critically evaluate the report generated by in silico variant analysis tools
  • Demonstrate the interrogation of population level genomic databases with respect to a specific genetic variant
  • Demonstrate the interrogation of mutation databases with respect to a specific genetic variant
  • Critically evaluate the medical literature regarding a specific genetic variant

Communication of genetic information and ethics

  • Communicate complex genetic data to patients/families effectively and sensitively
  • Critically evaluate the ethical issues surrounding consent for genetic testing with an understanding and explanation of incidental findings.
  • Communicate complex information about variants of unknown significance effectively to patients/families
  • Evaluate the ethical considerations of genetic testing and be able to formulate cogent arguments for and against testing in specific clinical scenarios

Personal and professional development portfolio

  • Assemble a portfolio that demonstrates learning and progression in the application of genetic technologies, the interpretation of genomic data and the communication of complex genetic information to patients
  • Demonstrate application of the approaches undertaken in the clinical interpretation of genomic data
  • Critically appraise the medical literature relevant to the interpretation of genetic data
  • Reflect on the effect of genetic test results on the patient and other healthcare professionals
  • Reflect on their communication skills when imparting complex genetic information to patients/families and the language that should be used in the development of patient/family directed literature
  • Propose and justify approaches to continuing professional development

Last Updated: Wednesday, 13 July 2016 12:10

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