Our research addresses time trends and inequalities in the burden of ill-health. We focus on respiratory conditions, cardiovascular disease and diabetes, disorders of vision, and deaths from addictive substances. We have a special interest in ethnic variations in health and its determinants among children.
As founder members of the International Study of Asthma and Allergies in Childhood (ISAAC), we have been involved for over 25 years in measuring the burden of respiratory disease nationally and globally.
Cardiovascular disease and diabetes
Through international collaborations including the MedCHAMPS project, we have evaluated which policies are likely to be the most cost-effective in reducing the burden of cardiovascular disease and diabetes in low and middle-income countries.
The RESCAP-MED project, a successor to MedCHAMPS, is building sustainable public health research capacity for studies of non-communicable diseases in the Mediterranean region. The implications of the worldwide epidemic of diabetes for the control of tuberculosis are currently being studied by the TANDEM collaboration.
Disorders of vision
Novel statistical approaches have been used to combine the results of studies from around the world, to assess geographical variations and time trends in the occurrence of short-sightedness in children and macular degeneration in older adults.
Data on mortality among drug users and addicts has been gathered by St George’s since the late 1960s and developed into the National Programme on Substance Abuse Deaths (NPSAD).
For many years we have had a special interest in monitoring deaths due to volatile substances such as glues and gases.
The Substance Misuse in the Undergraduate Medical Curriculum project aims to improve the education of future doctors in substance misuse issues, and has developed guidance and resources on integrating substance misuse into the undergraduate medical curriculum.
The ethnically diverse communities of South West London and elsewhere in the UK have been studied to document and explain differences between ethnic groups in risk factors for diabetes and cardiovascular disease, particularly heart and health risks in children.
Projects and publications
Recently funded projects
|Title||Funded by||Principal investigator or lead at St George's|
|The Respiratory Health of the Nation||British Lung Foundation||Professor David Strachan|
|A systematic overview of geographic variations and time trends in the prevalence of childhood myopia: implications for aetiology and early prevention||BUPA Foundation||Dr Alicja Rudnicka|
|RESCAP-MED (NCDs and their social determinants in Mediterranean countries: building sustainable research capacity for effective policy intervention)||European Union||Professor Julia Critchley|
|Tuberculosis and Diabetes: Quantifying the adverse impact of rising diabetes prevalence on tuberculosis global burden, and estimating the impact of targeted interventions on tuberculosis transmission||Qatar National Research Fund||Professor Julia Critchley|
|TANDEM (Concurrent Tuberculosis and Diabetes Mellitus: unravelling the causal link and improving care)||European Union||Professor Julia Critchley|
|Investigating the early emergence of ethnic differences in type 2 diabetes risk in UK South Asian, African-Caribbean and white European children: the role of childhood and early life factors||BUPA Foundation||Professor Peter Whincup|
|Emerging ethnic differences in type 2 diabetes risk in children of South Asian, African-Caribbean and European origin: the role of early life factors||Diabetes UK||Professor Peter Whincup|
Selected recent publications
Strachan DP, Aït-Khaled N, Foliaki S, Mallol J, Odhiambo J, Pearce N, Williams HC; The ISAAC Phase Three Study Group. Siblings, Asthma, rhinoconjunctivitis and eczema: a worldwide perspective from the International Study of Asthma and Allergies in Childhood. Clin Exp Allergy 2015;45:126-36.
Critchley J, Zaman S, Maziak W. MedCHAMPS: Mediterranean studies of cardiovascular disease and hyperglycaemia: analytical modelling of population socio-economic transitions. Int J Public Health 2015;60 Suppl 1:S1-2.
Rudnicka AR, Kapetanakis VV, Jarrar Z, Wathern AK, Wormald R, Fletcher AE, Cook DG, Owen CG. Incidence of late-stage age-related macular degeneration in American whites: Systematic review and meta-analysis. Am J Ophthalmol 2015;160:85-93.e3.
Butland BK, Field-Smith ME, Ramsey JD, Anderson HR. Twenty-five years of volatile substance abuse mortality: a national mortality surveillance programme. Addiction 2013;108:385-393.
Nightingale CM, Rudnicka AR, Owen CG, Donin AS, Newton SL, Furness CA, Howard EL, Gillings RD, Wells JC, Cook DG, Whincup PH. Are ethnic and gender specific equations needed to derive fat free mass from bioelectrical impedance in children of South Asian, black African-Caribbean and white European origin? Results of the assessment of body composition in children study. PLoS One 2013;8:e76426.