Our researchers collaborate together and worldwide to understand age-related disorders and improve their management.
The rise of age-related diseases research
Demographic changes towards an older European population are driving major and continent-wide changes in medical priorities towards age-related diseases.
Our work focuses on two of the most important and prevalent of these - cardiovascular diseases and dementia - as well as on cell senescence, which is emerging as a fundamental process common to many such age-related pathologies.
Senescence is genetically linked to the major diseases of ageing including cardiovascular disease, neurodegeneration, cancer and diabetes, and is strongly implicated as a causal process in ageing.
Our research methods
Diseases under study include:
- cardiovascular conditions like heart failure, atherosclerosis and stroke
- general conditions like cancer and chronic skin ulcers
- dementias including Alzheimer’s
Our basic and clinical researchers use a broad range of cutting-edge approaches. These include advanced molecular and cellular techniques through human and animal genetics, magnetic resonance imaging (MRI) and clinical trials.