Professor Shirley Hodgson is a specialist in genetics.
Her research interests include genetic cancer susceptibility, colorectal and breast cancers, endometrial cancer in women with Lynch Syndrome (HNPCC), Mirena IUS, carcinogenesis in colorectal polyps.
Her current projects include a collaboration with colleagues in Nepal Medical College, notably Dr Manohar Lal Shresthra, to ascertain individuals with novel genetic disorders from isolated inbred communities, for genetic studies in collaboration with Professor Andrew Crosby at SGUL. Her team are also testing families with multiple cases of papillary thyroid cancer for genetic variants which could contribute to a susceptibility to this cancer.
As part of a multidisciplinary clinic, with Dr Gul Bano at St Georges, the group is ascertaining individuals with novel syndromes causing a susceptibility to endocrine tumours and paragangliomas, with the aim of identifying new genetic endocrine tumour susceptibility genes and optimising management protocols for these individuals.
1998-2003 Reader in Clinical Genetics KCL and Honorary Consultant, Guy’s and St Thomas’ Hospital NHS Trust.
1990-1998 Senior Lecturer in Clinical Genetics, Division of Medical and Molecular Genetics, United Medical and Dental Schools of Guy’s and St Thomas’s Hospitals (UMDS, now GKT) and Honorary Consultant Clinical Geneticist, South Thames (East) Regional Genetics Centre, Guy’s and St Thomas’ Hospital NHS Trust, Guy’s Hospital.
1990-1996 Honorary Senior Lecturer in Clinical Genetics, St Mark’s Hospital and St Bartholomew’s Hospital and Director of Family Cancer Clinic, St Mark’s Hospital, Northwick Park.
1988-1990 Consultant Clinical Geneticist, East Anglian Regional Genetics Centre, Addenbrooke’s Hospital, Cambridge.
1983-1988 Senior Registrar (Clinical Genetics), South Thames (East) Regional Genetics Centre, Guy’s Hospital and Honorary Senior Registrar at Hammersmith Hospital, London.
Novelli MR, Williamson JA, Tomlinson IPM, Elia G, HODGSON SV, Talbot IC, Bodmer WF, Wright NA. (1996). Polyclonal origin of colonic adenomas in an XO/XY patient with FAP. Science 272, 1187-1190.
Brinkman H, Barwell J, Rose S, Tinworth L, Sodha N, Langman C, Brooks L, Payne S, Fisher S, Rowan A, Tomlinson I, HODGSON S. (2006) Evidence against a major genetic basis for combined breast and colorectal cancer susceptibility. Clin Genet. 70(6):526-9.
Docherty Z, Georgiou A, Langman C, Kesterton I, Rose S, Camplejohn R, Ball J, Barwell J, Gilchrist R, Pangon L, Berg J, HODGSON S (2007). Is chromosome radiosensitivity and apoptotic response to irradiation correlated with cancer susceptibility? Int J Radiat Biol. Jan;83(1):1-12.
Barwell J, Pangon L, Georgiou A, Kesterton I, Langman C, Arden-Jones A, Bancroft E, Salmon A, Locke I, Kote-Jarai Z, Morris JR, Solomon E, Berg J, Docherty Z, Camplejohn R, Eeles R, HODGSON SV.(2007 ). Lymphocyte radiosensitivity in BRCA1 and BRCA2 mutation carriers and implications for breast cancer susceptibility. Int J Cancer.121(7) 1631-6.
Barwell J, Pangon L, Georgiou A, Docherty Z, Kesterton I, Ball J, Camplejohn R, Berg J, Aviv A, Gardner J, Kato BS, Carter N, Paximadas D, Spector TD, HODGSON S. (2007). Is telomere length in peripheral blood lymphocytes correlated with cancer susceptibility or radiosensitivity? Br J Cancer. 97(12):1696-700.
Ismail Alrashdi, Samantha Levine, Joan Paterson, Rohit Saxena, Soonie R. Patel, Sarita Depani, Darren R. Hargrave, Kathy Pritchard-Jones and SHIRLEY V HODGSON. Hereditary leiomyomatosis and renal cell carcinoma: very early diagnosis of renal cancer in a paediatric patient. Fam Cancer. 2010 Jun;9(2):239-43.
Andrew D Beggs, Andrew R Latchford, Hans FA Vasen, Gabriella Moeslein, Angel Alonso, Stefan Aretz, Lucio Bertario, Ignacio Blanco, Steffen Bulow, John Burn, Gabriel Capella, Chrystelle Colas, Waltraut Friedl, Pal Moller, Frederick Hess, Heikki Jarvinen, Jucca-Pekka Mecklin, Fokko M Nagengast, Yann Parc, Robin KS Phillips, Warren Hyer, Maurizio Ponz de Leon, Laura Renkonen-Sinisalo, Julian Sampson, Astrid Stormorken, Sabine Tejpar, Huw Thomas, Juul T Wijnen, Sue Clark, and SHIRLEY V HODGSON (2010). Peutz-Jeghers Syndrome: a systematic review and recommendations for management. Gut;59(7):975-986. doi:10.1136/gut.2009.198499.
Professor Andrew Crosby, St George's, University of London
Ian Tomlinson, Oxford University
Mr Muti Abulafi, Mayday Hospital, London
Dr. Manohar lal Shresthsa, Nepal Medical College