Dr Phillip Hay has a particular interest in infections in women and pregnancy. He has studied the relationship between bacterial vaginosis and adverse pregnancy outcomes.
With Professor Cathy Ison, he developed the Hay-Ison criteria for interpreting gram-stained vaginal smears, which are used widely to diagnose bacterial vaginosis. He drafts national guidelines.
Dr Hay has performed many studies of diagnostic assay for genital infections and sexually transmitted infections (STIs), as well as clinical trials of treatments for most STIs. He works in the eSTI2 consortium led by his colleague Dr Tariq Sadiq. He has a successful collaboration with Dr Pippa Oakeshott (Community Health Sciences) performing studies on infections in early pregnancy and the prevention of pelvic infection trial of chlamydia screening. This group also collaborates with Professor Jurgen Jensen, Statens Serum Institiut, Copenhagen.
Dr Hay leads the clinical trials team in the Courtyard Clinic and has been principal investigator in more than 30 phase two, three,and four studies of antiretroviral agents and treatments for HIV and its complications. He has published several studies of pharmacokinetics in HIV+ve pregnant women.
Dr Hay has been at St George’s, University of London since 1992, based in the Courtyard Clinic. He was previously a Medical Research Council Clinical Fellow working with Professor David Taylor-Robinson at the Clinical Research Centre Northwick Park and the Jefferiss Wing, St Mary’s Hospital, Paddington. He completed his undergraduate training at St Thomas’s Hospital in 1983.
As well as unselected HIV and sexual health clinics he leads a pregnancy/mother and baby HIV clinic, and participates in the family HIV clinic. He drafts national guidelines for the British Association for Sexual Health and HIV (BASSH) on bacterial vaginosis and is on the writing committee for the British HIV Association (BHIVA) guideline for HIV in pregnant women.
Frequency and risk factors for prevalent, incident, and persistent genital carcinogenic human papillomavirus infection in sexually active women: community based cohort study. Oakeshott, P., Aghaizu, A., Reid, F., Howell-Jones, R., Hay, P. E., Sadiq, S. T., . . . Soldan, K. (2012). BMJ, 344, e4168.
Timing of progression from Chlamydia trachomatis infection to pelvic inflammatory disease: a mathematical modelling study. Herzog, S. A., Althaus, C. L., Heijne, J. C., Oakeshott, P., Kerry, S., Hay, P., . Low, N. (2012). BMC Infect Dis, 12, 187. doi:10.1186/1471-2334-12-187
Raltegravir in the prevention of mother-to-child transmission of HIV-1: effective transplacental transfer and delayed plasma clearance observed in preterm neonates. Hegazi, A., Mc Keown, D., Doerholt, K., Donaghy, S., Sadiq, S. T., & Hay, P. (2012). .
AIDS, 26(18), 2421-2423.doi:10.1097/QAD.0b013e32835a9aeb
Atazanavir in pregnancy: a report of 155 cases
Samuel M, Bradshaw D, Perry M, Dhairyawan R, Chan SY, Byrne L, Smith K, Zhou J, Hay P, Naftalin C, Offodile N, et al.
HIV Med 12:9-10 Apr 2011
Randomised controlled trial of screening for Chlamydia trachomatis to prevent pelvic inflammatory disease: the POPI (prevention of pelvic infection) trial. Oakeshott P, Kerry S, Aghaizu A, Atherton H, Hay S, Taylor-Robinson D, Simms I, Hay P. BMJ. 2010;340:c1642. doi: 10.1136/bmj.c1642.
High neonatal concentrations of raltegravir following transplacental transfer in HIV-1 positive pregnant women.
McKeown DA, Rosenvinge M, Donaghy S, Sharland M, Holt DW, Cormack I, Hay P, Sadiq ST. AIDS. 2010;24:2416-8.
Life in the littoral zone: Lactobacilli losing the plot Hay P Sex Transm Infect. 2005; 81: 100-2
Effect of early oral clindamycin on late miscarriage and preterm delivery in asymptomatic women with abnormal vaginal flora and bacterial vaginosis: a randomised controlled trial. Ugwumadu A, Manyonda I, Reid F, Hay P. Lancet 2003;361:983-8.
Abnormal bacterial colonisation of the genital tract as a marker for subsequent preterm delivery and late miscarriage. Hay PE, Lamont RF, Taylor Robinson D, Morgan DJ, Ison C, Pearson J. British Medical Journal 1994; 308: 295-298
Dr Hay is a member of Dr Tariq Sadiq’s research group and a reader in sexual health and HIV medicine.
Other members of the eSTI2 Consortium
Professor Jurgen Jensen, Statens Serum Institiut, Copenhagen
Dr Hay is currently funded by the Medical Research Counci (UK).
Dr Hay teaches undergraduate students on the subjects of sexually transmitted infections and HIV.
Dr Hay supervises postgraduate PhD students.