Professor Mike Sharland is one of the UK and Europe’s leading experts in antimicrobial prescribing, resistance and healthcare associated infection in children.
He chairs the Department of Health’s Expert Advisory Body on antimicrobial resistance and healthcare associated infection (ARHAI). He is the paediatric advisor on the ECDC expert committee ESAC-net and the joint ECDC/CDC Transatlantic Task Force of Antimicrobial Resistance (TATFAR). He is the lead clinical advisor to the BNF for Children on anti-infectives. He chairs the RCPCH Standing Committee on Infection and Immunisation.
He co-chairs PENTA-ID, the EMA Level 1 recognised clinical trials network on antimicrobials in Europe. PENTA-ID provides paediatric CT expertise to the IMI ND4BB new antibiotic clinical trial development programme. He has developed the Paediatric Infectious Diseases Unit at St George’s into a recognised Centre of excellence for clinical care, teaching and research. He was appointed Professor of Paediatric Infectious Diseases in November 2010.
Professor Sharland’s principal research interest is optimising the best use of antimicrobials in children. He has a long standing interest in developing the evidence base for the use of all paediatric antimicrobials and has developed a clear research strategy using both cohort studies and clinical trials to improve the evidence base for antimicrobial prescribing. He leads a wide number of clinical projects in the UK and Europe with active NIHR/Charity/DG SANCO and FP7 funding.
Professor Sharland has consultancy expertise in engaging individuals, small research groups and larger established research entities, with the purpose of creating and leading national and international networks of scientific collaborators in the field of antimicrobial prescribing.
Sharland M, Kendall H, Yeates D et al. Antibiotic prescribing in general practice and hospital admissions for peritonsillar abscess, mastoiditis, and rheumatic fever: a time trend analysis. BMJ 2005:331:328-329.
Menson EN, Walker AS, Sharland M, Wells C, Tudor-Williams G, Riordan FA, Lyall EG, Gibb DM; Collaborative HIV Paediatric Study Steering Committee. Underdosing of antiretrovirals in UK and Irish children with HIV as an example of problems in prescribing medicines to children, 1997-2005: cohort study. BMJ. 2006 May 20;332(7551):1183-7.
Sharland M; SACAR Paediatric Subgroup. The use of antibacterials in children: a report of the Specialist Advisory Committee on Antimicrobial Resistance (SACAR) Paediatric Subgroup. J Antimicrob Chemother. 2007 Aug;60 Suppl 1:i15-26.
Thompson PL, Gilbert RE, Long PF, Saxena S, Sharland M, Wong IC. Has UK guidance affected general practitioner antibiotic prescribing for otitis media in children? J Public Health. 2008 Dec;30(4):479-86.
Thompson PL, Gilbert RE, Long PF, Saxena S, Sharland M, Wong IC. Effect of antibiotics for otitis media on mastoiditis in children: a retrospective cohort study using the United kingdom general practice research database. Pediatrics. 2009 Feb;123(2):424-30.
Saxena S, Bottle A, Gilbert R, Sharland M. Increasing short-stay unplanned hospital admissions among children in England; time trends analysis '97-'06. PLoS One. 2009 Oct 15;4(10)
PENTA - Paediatric European Network for the Treatment of AIDS
ESPID - European Society of Paediatric Infectious Diseases
ECDC – European Centre for Disease prevention and Control
Erasmus University, Department of Epidemiology
ESAC team at University of Antwerp
Health Protection Agency (UK)
University of London School of Pharmacy
St George's Paediatric Infectious Diseases Research Group current projects:
Pedigan application (FP7)
NeoVanc application (FP7)
Paediatric Infectious Diseases Unit, St George’s Healthcare Trust current projects:
EU funding bodies including: