Professor Julia Critchley is Professor of Epidemiology in the Population Health Research Institute.
She has broad interests in cardiovascular and diabetes epidemiology, and in exploring the public health implications of associations between chronic and infectious diseases (tuberculosis and diabetes).
At the University of Liverpool, Professor Critchley developed a coronary heart disease (CHD) mortality model, (IMPACT with Professor Simon Capewell), which has since been widely replicated and refined. She was first author on several UK publications using the model, and led initial work looking at a middle income setting in Beijing where CHD mortality was rising. Professor Critchley has also managed projects carrying out secondary analyses of a large household survey assessing trends in smoking prevalence, looking also at the economic impact of smoking on households in China.
She won prestigious EC funding (2.7 million Euros, seven international partners, 2009-2013) to evaluate the national policy situation and cost-effectiveness of different policy options for coronary heart disease and diabetes prevention in four middle income, North Africa and Eastern Mediterranean countries (Palestine, Syria, Tunisia, Turkey); the MedCHAMPS project (Mediterranean Studies of Cardiovascular disease and Hyperglycaemia: Analytical Modelling of Population Socio-economic transitions; She is continuing this collaboration as a co-investigator on a follow-up project to strengthen research capacity for public health and non-communicable disease in this region; RESCAP-MED.
Professor Critchley is also developing a research programme focused on common chronic and infectious diseases such as tuberculosis (TB). She recently commenced a new EC FP funded consortium; TANDEM (Concurrent Tuberculosis and Diabetes Mellitus). This project is investigating:
the best ways to diagnose diabetes in TB patients and TB in diabetes patients
the costs of implementing these screenings and resulting treatment
the reasons why many TB patients with diabetes sometimes do not respond well to drug treatment
whether there are any genes that change the interaction between TB and type 2 diabetes
Professor Critchley joined the Population Health Research Institute in September 2010 to develop research collaborations in cardiovascular disease and diabetes epidemiology. Professor Critchley holds a PhD in Epidemiology (Oxford University) and Masters in Public Health (University of London). She has a broad background in statistical and cardiovascular disease epidemiology, including the development of modelling approaches to explain disease trends in different populations, particularly for cardiovascular diseases. She also has experience in UK and international public health, and evidence-based medicine gained over a period of 15 years in both UK service public health and in the university sector. She has 100 peer-reviewed publications, many as first or last author in high impact journals.
Professor Critchley graduated in Human Sciences at St John's College, Oxford in 1992 and went on to complete a PhD in HIV Epidemiology and Transmission Dynamics (1996). She worked for the NHS (public health services) in London, developing local public health services and research projects from 1996-1999. During this time she managed an HTA funded primary care physical activity promotion Trial; (EXERT).
Professor Critchley was appointed as a postdoctoral research fellow at the University of Liverpool in 2000, where she developed methodological expertise in coronary heart disease modelling, and in systematic reviews methodology. In 2006 she was promoted to Senior Lecturer at Newcastle University, where she developed a work programme (ARCHES) aimed at improving the prevention and treatment of non-communicable diseases in low and middle income settings.
Professor Critchley was the scientific co-ordinator of MedCHAMPS, an EC FP7 (European Commission funded) project to identify the policies most likely to be effective and feasible in preventing the burden of cardiovascular disease and diabetes in the Middle East. She is continuing this collaboration as a co-investigator on a follow-up project, RESCAP-MED.
Critchley JA, Young F, Orton L, Garner P. Corticosteroids for preventing mortality among people with tuberculosis: systematic review and meta-analysis. Lancet Infect Dis. 2013 Mar;13(3):223-37.
Saidi O, Ben Mansour N, O’Flaherty M, Capewell S, Critchley JA, et al. (2013) Analyzing Recent Coronary Heart Disease Mortality Trends in Tunisia between 1997 and 2009. PLoS ONE 8(5): e63202. doi:10.1371/journal.pone.0063202
Brown N, Critchley J, Bogowicz P, Mayige M, Unwin N. Risk scores based on self-reported or available clinical data to detect undiagnosed Type 2 Diabetes: a systematic review. Diabetes Res Clin Pract Volume 98, Issue 3, December 2012, Pages 369–385
Corris V, Unwin NC, Critchley JA. Quantifying the Association between Tuberculosis and Diabetes in the U.S.: A Case-Control Analysis. Chronic Illn 8(2):121-134 Jun 2012
Young F, Wotton CJ, Critchley JA, Unwin NC, Goldacre MJ. Increased risk of tuberculosis disease in people with diabetes mellitus: record-linkage study in a UK population. J Epidemiol Community Health 66(6):519-523 Jun 2012
Bowman S, Unwin N, Critchley J, Capewell S, Husseini A, Maziak W, Zaman S, Ben Romdhane H, Fouad F, Phillimore P, Unal B, Khatib R, Shoaibi A, Ahmad B. Use of evidence to support healthy public policy: a policy effectiveness–feasibility loop. Bulletin of the WHO; 2012: 90 (11). 847 - 853
Diabetes and the risk of tuberculosis: a neglected threat to public health? Stevenson CR, Critchley JA, Forouhi NG, Roglic G, Williams BG, Dye C, Unwin NC. Chronic Illn. 2007 Sep;3(3):228-45. Review.
ES Ford, UA Ajani, JB Croft, JA Critchley, DR Labarthe, TE Kottke, WH Giles, S Capewell. Explaining the Decrease in US deaths from Coronary Disease, 1980 -2000. NEJM 2007; 356: 2388-2398. http://dx.doi.org/10.1056/NEJMsa053935
Critchley JA, Liu J, Dong Z, Wei W, Capewell S. Explaining the increase in coronary heart disease mortality in Beijing between 1984 and 1999. Circulation 2004 110: 1236 – 1244
Professor Simon Capewell - (The University of Liverpool)
Professor Nigel Unwin - (University of the West Indies)
Prof Peter Phillimore - (Institute of Health and Society, Newcastle University)
Susanne Logstrup - European Heart Network
Dr Reinout van Crevel - (Radboud University Nijmegen Medical Centre)
2013 to 2017 (€6 million). TANDEM (Concurrent Tuberculosis and Diabetes Mellitus; unraveling the causal link, and improving care). PI Hazel Dockrell. Leader for WP1 – Screening TB patients for DM.
March 2011 to February 2014. European Commission Executive Agency for Health and Consumers (€2.1 million) Euroheart II (PI Susanne Logstrup, European Heart Network). WP leader for WP6 – Predicting future CVD trends under different policy scenarios in the EU: IMPACT CVD 2020 (approx Euros 787,000).
January 2012 to December 2014 (EC FP 7 – €1.98 million) RESCAP-MED (NCDs and their social determinants in Mediterranean countries: building sustainable research capacity for effective policy intervention). (PI Peter Phillimore, Newcastle University). WP leader for WP5 – Co-ordinating Web Based Resources.
March 2009 – February 2013 European Commission FP7 (€2.7 million) MEDCHAMPS (Mediterranean studies of Cardiovascular disease and Hyperglycaemia: Analytical Modelling of Population Socio-economic transitions), PrincipaI Investigator (co-applicants Nigel Unwin, Simon Capewell, Wasim Maziak, Kathleen Bennett, Belgin Unal, Awad Mataria, Habiba Ben Romdhane and colleagues).
NPRI 3 Prevention IMPACT: developing and evaluating economic models for planning cardiovascular disease prevention in individuals and populations (co-investigator, PI S Capewell) MRC 2009-2014 (£650,000) (Simon Capewell PI, with J Critchley, I Buchan , M O’Flaherty, C Donaldson et al).
May 2006-2008 IDRC Canada (£40,000), Active and passive smoking in China: analysis of data from the Chinese National Household surveys, PrincipaI Investigator (co-applicants Jun Gao, Shenglan Tang)
Integrated MRC MRes/PhD studentship (50% funded, approx. £48,000 - Fiona Young) 2007-2011 to develop a work programme around TB-Diabetes interactions Joint PrincipaI Investigator with Nigel Unwin.
July 2008-2012 Department of Health, Public Health Research Consortium (£59,950) An economic evaluation of change in school food policy (co-investigator, PI Nigel Armstrong, with Ashley Adamson, Steve Rushton, Cam Donaldson)
October 2006. European Commission PHEA 2007–9. (€1,200,000) DYNAMO HIA modelling tool, collaborator. (PI J Mackenbach, Erasmus) (ADONIS code 800193). Prof.dr. J.P. Mackenbach (PI); W Nusselder, J. L Veerman, H Boshuizen, J Smit, T Feenstra, L Den Broeder, R Hoogenveen, T Lobstein, M Mckee, J Pomerleau, E Fernandez, K Bennett, S Capewell, J Critchley, A Micheli.
May 2005 December 2008 – MRC. (£405,000) Extending the IMPACT coronary heart disease model to different health policy contexts (Co-Applicant, PI Simon Capewell, with Iain Buchan, James Raftery, P Whincup, C Sanderson, and colleagues).
December 2008 – 2009 (£160,000). South of Tyne PCT. Developing a tool for communication of vascular screening results. (co-investigator, PI Richard Thomson, with Bob Sugden, Martin Eccles, Aad Van Moorsel, Mark Lambert).
Professor Julia Critchley teaches as part of the intercalculated BSc/Biomedical Science BSc year 3 – Human Cardiovascular and Respiratory Epidemiology modules. She also teaches the Medicine MBBS – Case Analysis Project.
Professor Critchley is the module leader postgraduate diploma Physician Assistant Studies Evidence Based Practice module.