Dr Henry Staines is a Senior Research Fellow at St George's.
His research interests include transmembrane solute transport in apicomplexan parasites. He is a member of the St George's Molecular and Medical Parasitology Group.
His research methods include functional transport assays (radio-tracer, patch-clamp, fluorometric, haemolysis), parasite culture and heterologous protein expression.
Dr Staines studied a BSc in Biochemistry at the University of Kent at Canterbury. He then studied for a DPhil in Cellular Physiology at the University Laboratory of Physiology, Oxford.
During this time and his initial postdoctoral years, Dr Staines examined the transport mechanisms used by the malaria parasite, Plasmodium falciparum, to obtain nutrients and export waste products while developing within human red blood cells. Having been awarded a Wellcome Trust Research Career Development Fellowship, Dr Staines is now studying transport mechanisms in a wider range of unicellular parasites.
Honours and awards
2005-2009 Wellcome Trust RCD Fellowship
1997 The Peter Beaconsfield Prize
1996 Inaugural Oxford/ANU Exchange Programme student
HM Staines, S. Ashmore, H. Felgate, J. Moore, T. Powell and J. C. Ellory (2006). Solute transport via the new permeability pathways in Plasmodium falciparum-infected human red blood cells is not consistent with a simple single channel model. Blood, 108, 3187-3194
HM Staines, T. Powell, J. C. Ellory, S. Egée, F. Lapaix, G. Decherf, S. L. Y. Thomas, C. Duranton, F. Lang and S. M. Huber (2003). Modulation of whole-cell currents in Plasmodium falciparum-infected human red blood cells by holding potential and serum. J. Physiol., 552, 177-183
HM Staines, J. C. Ellory and K. Kirk (2001). Perturbation of the pump-leak balance for Na+ and K+ in malaria-infected erythrocytes. Am. J. Physiol., 280, C1576-C1587
Professor Kiaran Kirk ( Australian National University)
Professor Clive Ellory (University of Oxford)
Professor Trevor Powell (University of Oxford)
Dr Robert Wilkins (University of Oxford)
Dr Kelly Chibale (University of Capetown Medical School)